diff --git a/{{cookiecutter.project_slug}}/config/settings/local.py b/{{cookiecutter.project_slug}}/config/settings/local.py
index ab526f96..f6315123 100644
--- a/{{cookiecutter.project_slug}}/config/settings/local.py
+++ b/{{cookiecutter.project_slug}}/config/settings/local.py
@@ -64,7 +64,12 @@ INSTALLED_APPS += ["debug_toolbar"]
 MIDDLEWARE += ["debug_toolbar.middleware.DebugToolbarMiddleware"]
 # https://django-debug-toolbar.readthedocs.io/en/latest/configuration.html#debug-toolbar-config
 DEBUG_TOOLBAR_CONFIG = {
-    "DISABLE_PANELS": ["debug_toolbar.panels.redirects.RedirectsPanel"],
+    "DISABLE_PANELS": [
+        "debug_toolbar.panels.redirects.RedirectsPanel",
+        # Disable profiling panel due to an issue with Python 3.12:
+        # https://github.com/jazzband/django-debug-toolbar/issues/1875
+        "debug_toolbar.panels.profiling.ProfilingPanel",
+    ],
     "SHOW_TEMPLATE_CONTEXT": True,
 }
 # https://django-debug-toolbar.readthedocs.io/en/latest/installation.html#internal-ips