diff --git a/rest_framework/parsers.py b/rest_framework/parsers.py
index 2dc808f1a..4e0a83c5e 100644
--- a/rest_framework/parsers.py
+++ b/rest_framework/parsers.py
@@ -183,7 +183,7 @@ class FileUploadParser(BaseParser):
 
         for index, handler in enumerate(upload_handlers):
             file_obj = handler.file_complete(counters[index])
-            if file_obj:
+            if file_obj is not None:
                 return DataAndFiles({}, {'file': file_obj})
         raise ParseError("FileUpload parse error - "
                          "none of upload handlers can handle the stream")