diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index c3c587cbf..6276dddcd 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -14,8 +14,6 @@ jobs:
     strategy:
       matrix:
         python-version:
-        - '3.6'
-        - '3.7'
         - '3.8'
         - '3.9'
         - '3.10'
@@ -37,18 +35,9 @@ jobs:
     - name: Install dependencies
       run: python -m pip install --upgrade codecov tox
 
-    - name: Install tox-py
-      if: ${{ matrix.python-version == '3.6' }}
-      run: python -m pip install --upgrade tox-py
-
     - name: Run tox targets for ${{ matrix.python-version }}
-      if: ${{ matrix.python-version != '3.6' }}
       run: tox run -f py$(echo ${{ matrix.python-version }} | tr -d .)
 
-    - name: Run tox targets for ${{ matrix.python-version }}
-      if: ${{ matrix.python-version == '3.6' }}
-      run: tox --py current
-
     - name: Run extra tox targets
       if: ${{ matrix.python-version == '3.9' }}
       run: |
diff --git a/README.md b/README.md
index cadfd73a5..d32fbc331 100644
--- a/README.md
+++ b/README.md
@@ -53,8 +53,8 @@ Some reasons you might want to use REST framework:
 
 # Requirements
 
-* Python 3.6+
-* Django 5.0, 4.2, 4.1, 4.0, 3.2, 3.1, 3.0
+* Python 3.8+
+* Django 5.0, 4.2
 
 We **highly recommend** and only officially support the latest patch release of
 each Python and Django series.
diff --git a/docs/index.md b/docs/index.md
index adc66226e..98cbf6a40 100644
--- a/docs/index.md
+++ b/docs/index.md
@@ -86,8 +86,8 @@ continued development by **[signing up for a paid plan][funding]**.
 
 REST framework requires the following:
 
-* Python (3.6, 3.7, 3.8, 3.9, 3.10, 3.11, 3.12)
-* Django (3.0, 3.1, 3.2, 4.0, 4.1, 4.2, 5.0)
+* Django (4.2, 5.0)
+* Python (3.8, 3.9, 3.10, 3.11, 3.12)
 
 We **highly recommend** and only officially support the latest patch release of
 each Python and Django series.
diff --git a/setup.py b/setup.py
index 40898b6c1..d2cfe877e 100755
--- a/setup.py
+++ b/setup.py
@@ -8,7 +8,7 @@ from io import open
 from setuptools import find_packages, setup
 
 CURRENT_PYTHON = sys.version_info[:2]
-REQUIRED_PYTHON = (3, 6)
+REQUIRED_PYTHON = (3, 8)
 
 # This check and everything above must remain compatible with Python 2.7.
 if CURRENT_PYTHON < REQUIRED_PYTHON:
@@ -83,18 +83,13 @@ setup(
     author_email='tom@tomchristie.com',  # SEE NOTE BELOW (*)
     packages=find_packages(exclude=['tests*']),
     include_package_data=True,
-    install_requires=["django>=3.0", 'backports.zoneinfo;python_version<"3.9"'],
-    python_requires=">=3.6",
+    install_requires=["django>=4.2", 'backports.zoneinfo;python_version<"3.9"'],
+    python_requires=">=3.8",
     zip_safe=False,
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Web Environment',
         'Framework :: Django',
-        'Framework :: Django :: 3.0',
-        'Framework :: Django :: 3.1',
-        'Framework :: Django :: 3.2',
-        'Framework :: Django :: 4.0',
-        'Framework :: Django :: 4.1',
         'Framework :: Django :: 4.2',
         'Framework :: Django :: 5.0',
         'Intended Audience :: Developers',
@@ -102,8 +97,6 @@ setup(
         'Operating System :: OS Independent',
         'Programming Language :: Python',
         'Programming Language :: Python :: 3',
-        'Programming Language :: Python :: 3.6',
-        'Programming Language :: Python :: 3.7',
         'Programming Language :: Python :: 3.8',
         'Programming Language :: Python :: 3.9',
         'Programming Language :: Python :: 3.10',
diff --git a/tox.ini b/tox.ini
index ffcbd6729..45429371d 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,10 +1,7 @@
 [tox]
 envlist =
-       {py36,py37,py38,py39}-django30
-       {py36,py37,py38,py39}-django31
-       {py36,py37,py38,py39,py310}-django32
-       {py38,py39,py310}-{django40,django41,django42,djangomain}
-       {py311}-{django41,django42,django50,djangomain}
+       {py38,py39,py310}-{django42,djangomain}
+       {py311}-{django42,django50,djangomain}
        {py312}-{django42,djanggo50,djangomain}
        base
        dist
@@ -17,11 +14,6 @@ setenv =
        PYTHONDONTWRITEBYTECODE=1
        PYTHONWARNINGS=once
 deps =
-        django30: Django>=3.0,<3.1
-        django31: Django>=3.1,<3.2
-        django32: Django>=3.2,<4.0
-        django40: Django>=4.0,<4.1
-        django41: Django>=4.1,<4.2
         django42: Django>=4.2,<5.0
         django50: Django>=5.0,<5.1
         djangomain: https://github.com/django/django/archive/main.tar.gz