diff --git a/rest_framework/serializers.py b/rest_framework/serializers.py
index 0d35fb327..34f315318 100644
--- a/rest_framework/serializers.py
+++ b/rest_framework/serializers.py
@@ -878,7 +878,7 @@ class ModelSerializer(Serializer):
 
         # Reverse fk or one-to-one relations
         for (obj, model) in meta.get_all_related_objects_with_model():
-            field_name = obj.field.related_query_name()
+            field_name = obj.get_accessor_name()
             if field_name in attrs:
                 related_data[field_name] = attrs.pop(field_name)
 
@@ -949,11 +949,12 @@ class ModelSerializer(Serializer):
             del(obj._m2m_data)
 
         if getattr(obj, '_related_data', None):
+            related_fields = dict(((f.get_accessor_name(), f) for f, m in obj._meta.get_all_related_objects_with_model()))
             for accessor_name, related in obj._related_data.items():
                 if isinstance(related, RelationsList):
                     # Nested reverse fk relationship
                     for related_item in related:
-                        fk_field = obj._meta.get_field_by_name(accessor_name)[0].field.name
+                        fk_field = related_fields[accessor_name].field.name
                         setattr(related_item, fk_field, obj)
                         self.save_object(related_item)
 
diff --git a/rest_framework/tests/test_serializer_nested.py b/rest_framework/tests/test_serializer_nested.py
index 029f8bffd..7114a0603 100644
--- a/rest_framework/tests/test_serializer_nested.py
+++ b/rest_framework/tests/test_serializer_nested.py
@@ -6,6 +6,7 @@ Doesn't cover model serializers.
 from __future__ import unicode_literals
 from django.test import TestCase
 from rest_framework import serializers
+from . import models
 
 
 class WritableNestedSerializerBasicTests(TestCase):
@@ -311,3 +312,37 @@ class ForeignKeyNestedSerializerUpdateTests(TestCase):
         serializer = self.AlbumSerializer(instance=original, data=data)
         self.assertEqual(serializer.is_valid(), True)
         self.assertEqual(serializer.object, expected)
+
+
+class NestedModelSerializerUpdateTests(TestCase):
+    def test_second_nested_level(self):
+        john = models.Person.objects.create(name="john")
+
+        post = john.blogpost_set.create(title="Test blog post")
+        post.blogpostcomment_set.create(text="I hate this blog post")
+        post.blogpostcomment_set.create(text="I love this blog post")
+
+        class BlogPostCommentSerializer(serializers.ModelSerializer):
+            class Meta:
+                model = models.BlogPostComment
+
+        class BlogPostSerializer(serializers.ModelSerializer):
+            comments = BlogPostCommentSerializer(many=True, source='blogpostcomment_set')
+            class Meta:
+                model = models.BlogPost
+                fields = ('id', 'title', 'comments')
+
+        class PersonSerializer(serializers.ModelSerializer):
+            posts = BlogPostSerializer(many=True, source='blogpost_set')
+            class Meta:
+                model = models.Person
+                fields = ('id', 'name', 'age', 'posts')
+
+        serialize = PersonSerializer(instance=john)
+        deserialize = PersonSerializer(data=serialize.data, instance=john)
+        self.assertTrue(deserialize.is_valid())
+
+        result = deserialize.object
+        result.save()
+        self.assertEqual(result.id, john.id)
+