diff --git a/rest_framework/serializers.py b/rest_framework/serializers.py
index 6d25161e2..f37fbf980 100644
--- a/rest_framework/serializers.py
+++ b/rest_framework/serializers.py
@@ -904,13 +904,11 @@ class ModelSerializer(Serializer):
             for attribute in attributes:
                 kwargs.update({attribute: getattr(model_field, attribute)})
 
-        try:
-            return self.field_mapping[model_field.__class__](**kwargs)
-        except KeyError:
-            for model_field_class, serializer_field_class in self.field_mapping.items():
-                if isinstance(model_field, model_field_class):
-                    return serializer_field_class(**kwargs)
-            return ModelField(model_field=model_field, **kwargs)
+        for model_field_baseclass in inspect.getmro(model_field.__class__):
+            serializer_field_class = self.field_mapping.get(model_field_baseclass)
+            if serializer_field_class:
+                return serializer_field_class(**kwargs)
+        return ModelField(model_field=model_field, **kwargs)
 
     def get_validation_exclusions(self, instance=None):
         """