diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index 48b6e7202..2dc186bcb 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -14,7 +14,6 @@ jobs:
     strategy:
       matrix:
         python-version:
-        - '3.6'
         - '3.7'
         - '3.8'
         - '3.9'
@@ -36,18 +35,9 @@ jobs:
     - name: Install dependencies
       run: python -m pip install --upgrade codecov tox
 
-    - name: Install tox-py
-      if: ${{ matrix.python-version == '3.6' }}
-      run: python -m pip install --upgrade tox-py
-
     - name: Run tox targets for ${{ matrix.python-version }}
-      if: ${{ matrix.python-version != '3.6' }}
       run: tox run -f py$(echo ${{ matrix.python-version }} | tr -d .)
 
-    - name: Run tox targets for ${{ matrix.python-version }}
-      if: ${{ matrix.python-version == '3.6' }}
-      run: tox --py current
-
     - name: Run extra tox targets
       if: ${{ matrix.python-version == '3.9' }}
       run: |
diff --git a/README.md b/README.md
index c2975a418..f66e5d940 100644
--- a/README.md
+++ b/README.md
@@ -54,7 +54,7 @@ There is a live example API for testing purposes, [available here][sandbox].
 
 # Requirements
 
-* Python 3.6+
+* Python 3.7+
 * Django 4.2, 4.1, 4.0, 3.2, 3.1, 3.0
 
 We **highly recommend** and only officially support the latest patch release of
diff --git a/docs/index.md b/docs/index.md
index 81a556313..4d264c36b 100644
--- a/docs/index.md
+++ b/docs/index.md
@@ -85,7 +85,7 @@ continued development by **[signing up for a paid plan][funding]**.
 
 REST framework requires the following:
 
-* Python (3.6, 3.7, 3.8, 3.9, 3.10, 3.11)
+* Python (3.7, 3.8, 3.9, 3.10, 3.11)
 * Django (3.0, 3.1, 3.2, 4.0, 4.1, 4.2)
 
 We **highly recommend** and only officially support the latest patch release of
diff --git a/setup.py b/setup.py
index 6afd5e05e..3fd9aeec6 100755
--- a/setup.py
+++ b/setup.py
@@ -8,7 +8,7 @@ from io import open
 from setuptools import find_packages, setup
 
 CURRENT_PYTHON = sys.version_info[:2]
-REQUIRED_PYTHON = (3, 6)
+REQUIRED_PYTHON = (3, 7)
 
 # This check and everything above must remain compatible with Python 2.7.
 if CURRENT_PYTHON < REQUIRED_PYTHON:
@@ -84,7 +84,7 @@ setup(
     packages=find_packages(exclude=['tests*']),
     include_package_data=True,
     install_requires=["django>=3.0", 'backports.zoneinfo;python_version<"3.9"'],
-    python_requires=">=3.6",
+    python_requires=">=3.7",
     zip_safe=False,
     classifiers=[
         'Development Status :: 5 - Production/Stable',
@@ -101,7 +101,6 @@ setup(
         'Operating System :: OS Independent',
         'Programming Language :: Python',
         'Programming Language :: Python :: 3',
-        'Programming Language :: Python :: 3.6',
         'Programming Language :: Python :: 3.7',
         'Programming Language :: Python :: 3.8',
         'Programming Language :: Python :: 3.9',