diff --git a/docs/main/changelog.rst b/docs/main/changelog.rst
index eebf8b67..81ece652 100644
--- a/docs/main/changelog.rst
+++ b/docs/main/changelog.rst
@@ -7,6 +7,10 @@ that were made in every particular version.
 From version 0.7.6 *Dependency Injector* framework strictly 
 follows `Semantic versioning`_
 
+Develop
+-------
+- Improve ``FastAPI`` integration: handle ``Depends(Provide[...])``.
+
 4.4.0
 -----
 - Add ``@inject`` decorator. It helps to fix a number of wiring bugs and make wiring be more resilient.
diff --git a/src/dependency_injector/wiring.py b/src/dependency_injector/wiring.py
index 1ba73639..6752f106 100644
--- a/src/dependency_injector/wiring.py
+++ b/src/dependency_injector/wiring.py
@@ -27,6 +27,13 @@ else:
         ...
 
 
+try:
+    from fastapi.params import Depends as FastAPIDepends
+    fastapi_installed = True
+except ImportError:
+    fastapi_installed = False
+
+
 from . import providers
 
 
@@ -320,10 +327,15 @@ def _fetch_reference_injections(
     injections = {}
     closing = {}
     for parameter_name, parameter in signature.parameters.items():
-        if not isinstance(parameter.default, _Marker):
+        if not isinstance(parameter.default, _Marker) \
+                and not _is_fastapi_depends(parameter.default):
             continue
+
         marker = parameter.default
 
+        if _is_fastapi_depends(marker):
+            marker = marker.dependency
+
         if isinstance(marker, Closing):
             marker = marker.provider
             closing[parameter_name] = marker
@@ -435,6 +447,10 @@ def _is_fastapi_default_arg_injection(injection, kwargs):
     return injection in kwargs and isinstance(kwargs[injection], _Marker)
 
 
+def _is_fastapi_depends(param: Any) -> bool:
+    return fastapi_installed and isinstance(param, FastAPIDepends)
+
+
 def _is_patched(fn):
     return getattr(fn, '__wired__', False) is True
 
@@ -459,6 +475,9 @@ class _Marker(Generic[T], metaclass=ClassGetItemMeta):
     def __class_getitem__(cls, item) -> T:
         return cls(item)
 
+    def __call__(self) -> T:
+        return self
+
 
 class Provide(_Marker):
     ...