diff --git a/setup.cfg b/setup.cfg
index e61ae94a2..9aeeab617 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -30,17 +30,6 @@ project_urls =
 zip_safe = false
 include_package_data = true
 python_requires = >=3.8
-# NOTE: This section is superseded by pyproject.toml and will be removed in
-# spaCy v4
-setup_requires =
-    cython>=0.25,<3.0
-    numpy>=1.15.0; python_version < "3.9"
-    numpy>=1.19.0; python_version >= "3.9"
-    # We also need our Cython packages here to compile against
-    cymem>=2.0.2,<2.1.0
-    preshed>=3.0.2,<3.1.0
-    murmurhash>=0.28.0,<1.1.0
-    thinc>=9.0.0.dev4,<9.1.0
 install_requires =
     # Our libraries
     spacy-legacy>=4.0.0.dev0,<4.1.0