diff --git a/graphene/pyutils/version.py b/graphene/pyutils/version.py
index f2005442..de329c43 100644
--- a/graphene/pyutils/version.py
+++ b/graphene/pyutils/version.py
@@ -3,6 +3,7 @@ from __future__ import unicode_literals
 import datetime
 import os
 import subprocess
+from ..utils.comparison_helper import raise_assertion_if
 
 
 def get_version(version=None):
@@ -44,8 +45,14 @@ def get_complete_version(version=None):
     if version is None:
         from graphene import VERSION as version
     else:
-        assert len(version) == 5
-        assert version[3] in ("alpha", "beta", "rc", "final")
+        raise_assertion_if(
+            condition=len(version) is not 5, message="Version needs to be 5"
+        )
+
+        raise_assertion_if(
+            condition=version[3] not in ("alpha", "beta", "rc", "final"),
+            message="Release version is unkown",
+        )
 
     return version
 
diff --git a/graphene/relay/connection.py b/graphene/relay/connection.py
index f23849f2..c195ae42 100644
--- a/graphene/relay/connection.py
+++ b/graphene/relay/connection.py
@@ -9,6 +9,7 @@ from ..types import Boolean, Enum, Int, Interface, List, NonNull, Scalar, String
 from ..types.field import Field
 from ..types.objecttype import ObjectType, ObjectTypeOptions
 from .node import is_node
+from ..utils.comparison_helper import raise_assertion_if
 
 
 class PageInfo(ObjectType):
@@ -46,12 +47,18 @@ class Connection(ObjectType):
     @classmethod
     def __init_subclass_with_meta__(cls, node=None, name=None, **options):
         _meta = ConnectionOptions(cls)
-        assert node, "You have to provide a node in {}.Meta".format(cls.__name__)
-        assert issubclass(
-            node, (Scalar, Enum, ObjectType, Interface, Union, NonNull)
-        ), ('Received incompatible node "{}" for Connection {}.').format(
+        error_message = "You have to provide a node in {}.Meta".format(cls.__name__)
+        raise_assertion_if(condition=not node, message=error_message)
+
+        error_message = 'Received incompatible node "{}" for Connection {}.'.format(
             node, cls.__name__
         )
+        raise_assertion_if(
+            condition=not issubclass(
+                node, (Scalar, Enum, ObjectType, Interface, Union, NonNull)
+            ),
+            error_message=error_message,
+        )
 
         base_name = re.sub("Connection$", "", name or cls.__name__) or node._meta.name
         if not name:
@@ -101,15 +108,20 @@ class IterableConnectionField(Field):
         if isinstance(type, NonNull):
             connection_type = type.of_type
 
-        if is_node(connection_type):
-            raise Exception(
-                "ConnectionField's now need a explicit ConnectionType for Nodes.\n"
-                "Read more: https://github.com/graphql-python/graphene/blob/v2.0.0/UPGRADE-v2.0.md#node-connections"
-            )
+        error_message = """
+            ConnectionField's now need a explicit ConnectionType for Nodes.
+            Read more: https://github.com/graphql-python/graphene/blob/v2.0.0/UPGRADE-v2.0.md#node-connections
+        """
+        raise_assertion_if(
+            condition=is_node(connection_type), error_message=error_message
+        )
 
-        assert issubclass(connection_type, Connection), (
-            '{} type have to be a subclass of Connection. Received "{}".'
-        ).format(self.__class__.__name__, connection_type)
+        error_message = '{} type have to be a subclass of Connection. Received "{}".'.format(
+            self.__class__.__name__, connection_type
+        )
+        raise_assertion_if(
+            condition=not issubclass(connection_type, Connection), message=error_message
+        )
         return type
 
     @classmethod
@@ -117,10 +129,16 @@ class IterableConnectionField(Field):
         if isinstance(resolved, connection_type):
             return resolved
 
-        assert isinstance(resolved, Iterable), (
-            "Resolved value from the connection field have to be iterable or instance of {}. "
-            'Received "{}"'
-        ).format(connection_type, resolved)
+        error_message = """
+            Resolved value from the connection field have to be iterable or instance of {}.
+            Received "{}"
+         """.format(
+            connection_type, resolved
+        )
+        raise_assertion_if(
+            condition=not isinstance(resolved, Iterable), message=error_message
+        )
+
         connection = connection_from_list(
             resolved,
             args,
diff --git a/graphene/relay/mutation.py b/graphene/relay/mutation.py
index 1b8b855e..211ee44f 100644
--- a/graphene/relay/mutation.py
+++ b/graphene/relay/mutation.py
@@ -18,8 +18,11 @@ class ClientIDMutation(Mutation):
         input_class = getattr(cls, "Input", None)
         base_name = re.sub("Payload$", "", name or cls.__name__)
 
-        assert not output, "Can't specify any output"
-        assert not arguments, "Can't specify any arguments"
+        if output:
+            raise AssertionError("Can't specify any output")
+
+        if arguments:
+            raise AssertionError("Can't specify any arguments")
 
         bases = (InputObjectType,)
         if input_class:
@@ -42,10 +45,12 @@ class ClientIDMutation(Mutation):
         )
         mutate_and_get_payload = getattr(cls, "mutate_and_get_payload", None)
         if cls.mutate and cls.mutate.__func__ == ClientIDMutation.mutate.__func__:
-            assert mutate_and_get_payload, (
-                "{name}.mutate_and_get_payload method is required"
-                " in a ClientIDMutation."
-            ).format(name=name or cls.__name__)
+            if not mutate_and_get_payload:
+                raise AssertionError(
+                    "{name}.mutate_and_get_payload method is required in a ClientIDMutation.".format(
+                        name=name or cls.__name__
+                    )
+                )
 
         if not name:
             name = "{}Payload".format(base_name)
diff --git a/graphene/relay/node.py b/graphene/relay/node.py
index d9c4c0f6..44020ae3 100644
--- a/graphene/relay/node.py
+++ b/graphene/relay/node.py
@@ -49,7 +49,8 @@ class GlobalID(Field):
 
 class NodeField(Field):
     def __init__(self, node, type=False, deprecation_reason=None, name=None, **kwargs):
-        assert issubclass(node, Node), "NodeField can only operate in Nodes"
+        if not issubclass(node, Node):
+            raise AssertionError("NodeField can only operate in Nodes")
         self.node_type = node
         self.field_type = type
 
@@ -98,9 +99,10 @@ class Node(AbstractNode):
             return None
 
         if only_type:
-            assert graphene_type == only_type, ("Must receive a {} id.").format(
-                only_type._meta.name
-            )
+            if graphene_type != only_type:
+                raise AssertionError(
+                    "Must receive a {} id.".format(only_type._meta.name)
+                )
 
         # We make sure the ObjectType implements the "Node" interface
         if cls not in graphene_type._meta.interfaces:
diff --git a/graphene/types/argument.py b/graphene/types/argument.py
index 9c75bcee..326e173d 100644
--- a/graphene/types/argument.py
+++ b/graphene/types/argument.py
@@ -73,11 +73,10 @@ def to_arguments(args, extra_args=None):
             raise ValueError('Unknown argument "{}".'.format(default_name))
 
         arg_name = default_name or arg.name
-        assert (
-            arg_name not in arguments
-        ), 'More than one Argument have same name "{}".'.format(
-            arg_name
-        )
+        if arg_name in arguments:
+            raise AssertionError(
+                'More than one Argument have same name "{}".'.format(arg_name)
+            )
         arguments[arg_name] = arg
 
     return arguments
diff --git a/graphene/types/base.py b/graphene/types/base.py
index aa97ed22..1b4d4034 100644
--- a/graphene/types/base.py
+++ b/graphene/types/base.py
@@ -31,7 +31,8 @@ class BaseType(SubclassWithMeta):
 
     @classmethod
     def __init_subclass_with_meta__(cls, name=None, description=None, _meta=None):
-        assert "_meta" not in cls.__dict__, "Can't assign directly meta"
+        if "_meta" in cls.__dict__:
+            raise AssertionError("Can't assign meta directly")
         if not _meta:
             return
         _meta.name = name or cls.__name__
diff --git a/graphene/types/datetime.py b/graphene/types/datetime.py
index 739032b0..3aa38c98 100644
--- a/graphene/types/datetime.py
+++ b/graphene/types/datetime.py
@@ -19,9 +19,8 @@ class Date(Scalar):
     def serialize(date):
         if isinstance(date, datetime.datetime):
             date = date.date()
-        assert isinstance(
-            date, datetime.date
-        ), 'Received not compatible date "{}"'.format(repr(date))
+        if not isinstance(date, datetime.date):
+            raise AssertionError('Received not compatible date "{}"'.format(repr(date)))
         return date.isoformat()
 
     @classmethod
@@ -46,9 +45,10 @@ class DateTime(Scalar):
 
     @staticmethod
     def serialize(dt):
-        assert isinstance(
-            dt, (datetime.datetime, datetime.date)
-        ), 'Received not compatible datetime "{}"'.format(repr(dt))
+        if not isinstance(dt, (datetime.datetime, datetime.date)):
+            raise AssertionError(
+                'Received not compatible datetime "{}"'.format(repr(dt))
+            )
         return dt.isoformat()
 
     @classmethod
@@ -73,9 +73,8 @@ class Time(Scalar):
 
     @staticmethod
     def serialize(time):
-        assert isinstance(
-            time, datetime.time
-        ), 'Received not compatible time "{}"'.format(repr(time))
+        if not isinstance(time, datetime.time):
+            raise AssertionError('Received not compatible time "{}"'.format(repr(time)))
         return time.isoformat()
 
     @classmethod
diff --git a/graphene/types/dynamic.py b/graphene/types/dynamic.py
index 588c53bb..d7747644 100644
--- a/graphene/types/dynamic.py
+++ b/graphene/types/dynamic.py
@@ -12,7 +12,10 @@ class Dynamic(MountedType):
 
     def __init__(self, type, with_schema=False, _creation_counter=None):
         super(Dynamic, self).__init__(_creation_counter=_creation_counter)
-        assert inspect.isfunction(type) or isinstance(type, partial)
+        if not (inspect.isfunction(type) or isinstance(type, partial)):
+            raise AssertionError(
+                "type is expected to be a function or an instance of partial"
+            )
         self.type = type
         self.with_schema = with_schema
 
diff --git a/graphene/types/field.py b/graphene/types/field.py
index a1428632..a42d131a 100644
--- a/graphene/types/field.py
+++ b/graphene/types/field.py
@@ -34,15 +34,21 @@ class Field(MountedType):
         **extra_args
     ):
         super(Field, self).__init__(_creation_counter=_creation_counter)
-        assert not args or isinstance(args, Mapping), (
-            'Arguments in a field have to be a mapping, received "{}".'
-        ).format(args)
-        assert not (
-            source and resolver
-        ), "A Field cannot have a source and a resolver in at the same time."
-        assert not callable(default_value), (
-            'The default value can not be a function but received "{}".'
-        ).format(base_type(default_value))
+
+        if args and not isinstance(args, Mapping):
+            raise AssertionError(
+                'Arguments in a field have to be a mapping, received "{}".'.format(args)
+            )
+        if source and resolver:
+            raise AssertionError(
+                "A Field cannot have a source and a resolver in at the same time."
+            )
+        if callable(default_value):
+            raise AssertionError(
+                'The default value can not be a function but received "{}".'.format(
+                    base_type(default_value)
+                )
+            )
 
         if required:
             type = NonNull(type)
diff --git a/graphene/types/mountedtype.py b/graphene/types/mountedtype.py
index 6d0c8cf8..fc4efb85 100644
--- a/graphene/types/mountedtype.py
+++ b/graphene/types/mountedtype.py
@@ -8,9 +8,10 @@ class MountedType(OrderedType):
         """
         Mount the UnmountedType instance
         """
-        assert isinstance(unmounted, UnmountedType), ("{} can't mount {}").format(
-            cls.__name__, repr(unmounted)
-        )
+        if not isinstance(unmounted, UnmountedType):
+            raise AssertionError(
+                "{} can't mount {}".format(cls.__name__, repr(unmounted))
+            )
 
         return cls(
             unmounted.get_type(),
diff --git a/graphene/types/objecttype.py b/graphene/types/objecttype.py
index be4addb2..2be97358 100644
--- a/graphene/types/objecttype.py
+++ b/graphene/types/objecttype.py
@@ -47,10 +47,15 @@ class ObjectType(BaseType):
         for base in reversed(cls.__mro__):
             fields.update(yank_fields_from_attrs(base.__dict__, _as=Field))
 
-        assert not (possible_types and cls.is_type_of), (
-            "{name}.Meta.possible_types will cause type collision with {name}.is_type_of. "
-            "Please use one or other."
-        ).format(name=cls.__name__)
+        if possible_types and cls.is_type_of:
+            raise AssertionError(
+                """
+                    {name}.Meta.possible_types will cause type collision with {name}.is_type_of.
+                    Please use one or other.
+                """.format(
+                    name=cls.__name__
+                )
+            )
 
         if _meta.fields:
             _meta.fields.update(fields)
diff --git a/graphene/types/resolver.py b/graphene/types/resolver.py
index 888aba8a..d9151b2a 100644
--- a/graphene/types/resolver.py
+++ b/graphene/types/resolver.py
@@ -11,7 +11,8 @@ default_resolver = attr_resolver
 
 def set_default_resolver(resolver):
     global default_resolver
-    assert callable(resolver), "Received non-callable resolver."
+    if not callable(resolver):
+        raise AssertionError("Received non-callable resolver.")
     default_resolver = resolver
 
 
diff --git a/graphene/types/schema.py b/graphene/types/schema.py
index a885c88a..9250f86d 100644
--- a/graphene/types/schema.py
+++ b/graphene/types/schema.py
@@ -20,9 +20,8 @@ def assert_valid_root_type(_type):
         return
     is_graphene_objecttype = inspect.isclass(_type) and issubclass(_type, ObjectType)
     is_graphql_objecttype = isinstance(_type, GraphQLObjectType)
-    assert is_graphene_objecttype or is_graphql_objecttype, (
-        "Type {} is not a valid ObjectType."
-    ).format(_type)
+    if not (is_graphene_objecttype or is_graphql_objecttype):
+        raise AssertionError("Type {} is not a valid ObjectType.".format(_type))
 
 
 class Schema(GraphQLSchema):
@@ -53,11 +52,12 @@ class Schema(GraphQLSchema):
         if directives is None:
             directives = [GraphQLIncludeDirective, GraphQLSkipDirective]
 
-        assert all(
-            isinstance(d, GraphQLDirective) for d in directives
-        ), "Schema directives must be List[GraphQLDirective] if provided but got: {}.".format(
-            directives
-        )
+        if not all(isinstance(d, GraphQLDirective) for d in directives):
+            raise AssertionError(
+                "Schema directives must be List[GraphQLDirective] if provided but got: {}.".format(
+                    directives
+                )
+            )
         self._directives = directives
         self.build_typemap()
 
@@ -91,10 +91,16 @@ class Schema(GraphQLSchema):
             return _type
         if is_graphene_type(_type):
             graphql_type = self.get_type(_type._meta.name)
-            assert graphql_type, "Type {} not found in this schema.".format(
-                _type._meta.name
-            )
-            assert graphql_type.graphene_type == _type
+            if not graphql_type:
+                raise AssertionError(
+                    "Type {} not found in this schema.".format(_type._meta.name)
+                )
+            if graphql_type.graphene_type != _type:
+                raise AssertionError(
+                    "The type {} does not match with the associated graphene type {}.".format(
+                        _type, graphql_type.graphene_type
+                    )
+                )
             return graphql_type
         raise Exception("{} is not a valid GraphQL type.".format(_type))
 
diff --git a/graphene/types/tests/test_objecttype.py b/graphene/types/tests/test_objecttype.py
index 2acb578f..d7cdd992 100644
--- a/graphene/types/tests/test_objecttype.py
+++ b/graphene/types/tests/test_objecttype.py
@@ -228,10 +228,13 @@ def test_objecttype_with_possible_types_and_is_type_of_should_raise():
             def is_type_of(cls, root, context, info):
                 return False
 
-    assert str(excinfo.value) == (
-        "MyObjectType.Meta.possible_types will cause type collision with "
-        "MyObjectType.is_type_of. Please use one or other."
-    )
+    assertion_message = """
+        MyObjectType.Meta.possible_types will cause type collision with MyObjectType.is_type_of.
+        Please use one or other.
+    """
+    space_removed_excinfo = str(excinfo.value).replace(" ", "")
+    space_removed_assertion_message = assertion_message.replace(" ", "")
+    assert space_removed_assertion_message == space_removed_excinfo
 
 
 def test_objecttype_no_fields_output():
diff --git a/graphene/types/typemap.py b/graphene/types/typemap.py
index dce04445..f34cd50e 100644
--- a/graphene/types/typemap.py
+++ b/graphene/types/typemap.py
@@ -60,10 +60,16 @@ def resolve_type(resolve_type_func, map, type_name, root, info):
 
     if inspect.isclass(_type) and issubclass(_type, ObjectType):
         graphql_type = map.get(_type._meta.name)
-        assert graphql_type, "Can't find type {} in schema".format(_type._meta.name)
-        assert graphql_type.graphene_type == _type, (
-            "The type {} does not match with the associated graphene type {}."
-        ).format(_type, graphql_type.graphene_type)
+        if not graphql_type:
+            raise AssertionError(
+                "Can't find type {} in schema".format(_type._meta.name)
+            )
+        if graphql_type.graphene_type != _type:
+            raise AssertionError(
+                "The type {} does not match with the associated graphene type {}.".format(
+                    _type, graphql_type.graphene_type
+                )
+            )
         return graphql_type
 
     return _type
@@ -94,9 +100,12 @@ class TypeMap(GraphQLTypeMap):
         if type._meta.name in map:
             _type = map[type._meta.name]
             if isinstance(_type, GrapheneGraphQLType):
-                assert _type.graphene_type == type, (
-                    "Found different types with the same name in the schema: {}, {}."
-                ).format(_type.graphene_type, type)
+                if _type.graphene_type is not type:
+                    raise AssertionError(
+                        "Found different types with the same name in the schema: {}, {}.".format(
+                            _type.graphene_type, type
+                        )
+                    )
             return map
 
         if issubclass(type, ObjectType):
@@ -173,9 +182,12 @@ class TypeMap(GraphQLTypeMap):
         if type._meta.name in map:
             _type = map[type._meta.name]
             if isinstance(_type, GrapheneGraphQLType):
-                assert _type.graphene_type == type, (
-                    "Found different types with the same name in the schema: {}, {}."
-                ).format(_type.graphene_type, type)
+                if _type.graphene_type != type:
+                    raise AssertionError(
+                        "Found different types with the same name in the schema: {}, {}.".format(
+                            _type.graphene_type, type
+                        )
+                    )
             return _type
 
         def interfaces():
@@ -183,7 +195,12 @@ class TypeMap(GraphQLTypeMap):
             for interface in type._meta.interfaces:
                 self.graphene_reducer(map, interface)
                 internal_type = map[interface._meta.name]
-                assert internal_type.graphene_type == interface
+                if internal_type.graphene_type != interface:
+                    raise AssertionError(
+                        "Found different types with the same name in the schema: {}, {}.".format(
+                            internal_type.graphene_type, interface
+                        )
+                    )
                 interfaces.append(internal_type)
             return interfaces
 
@@ -207,9 +224,12 @@ class TypeMap(GraphQLTypeMap):
         if type._meta.name in map:
             _type = map[type._meta.name]
             if isinstance(_type, GrapheneInterfaceType):
-                assert _type.graphene_type == type, (
-                    "Found different types with the same name in the schema: {}, {}."
-                ).format(_type.graphene_type, type)
+                if _type.graphene_type != type:
+                    raise AssertionError(
+                        "Found different types with the same name in the schema: {}, {}.".format(
+                            _type.graphene_type, type
+                        )
+                    )
             return _type
 
         _resolve_type = None
@@ -248,7 +268,12 @@ class TypeMap(GraphQLTypeMap):
             for objecttype in type._meta.types:
                 self.graphene_reducer(map, objecttype)
                 internal_type = map[objecttype._meta.name]
-                assert internal_type.graphene_type == objecttype
+                if internal_type.graphene_type != objecttype:
+                    raise AssertionError(
+                        "Found different types with the same name in the schema: {}, {}.".format(
+                            internal_type.graphene_type, objecttype
+                        )
+                    )
                 union_types.append(internal_type)
             return union_types
 
diff --git a/graphene/types/union.py b/graphene/types/union.py
index dc207e8e..1c14fd71 100644
--- a/graphene/types/union.py
+++ b/graphene/types/union.py
@@ -23,10 +23,10 @@ class Union(UnmountedType, BaseType):
 
     @classmethod
     def __init_subclass_with_meta__(cls, types=None, **options):
-        assert (
-            isinstance(types, (list, tuple)) and len(types) > 0
-        ), "Must provide types for Union {name}.".format(name=cls.__name__)
-
+        if not (isinstance(types, (list, tuple)) and len(types) > 0):
+            raise AssertionError(
+                "Must provide types for Union {name}.".format(name=cls.__name__)
+            )
         _meta = UnionOptions(cls)
         _meta.types = types
         super(Union, cls).__init_subclass_with_meta__(_meta=_meta, **options)
diff --git a/graphene/types/uuid.py b/graphene/types/uuid.py
index abb8f110..84089a2d 100644
--- a/graphene/types/uuid.py
+++ b/graphene/types/uuid.py
@@ -14,9 +14,8 @@ class UUID(Scalar):
     def serialize(uuid):
         if isinstance(uuid, str):
             uuid = _UUID(uuid)
-        assert isinstance(uuid, _UUID), "Expected UUID instance, received {}".format(
-            uuid
-        )
+        if not isinstance(uuid, _UUID):
+            raise AssertionError("Expected UUID instance, received {}".format(uuid))
         return str(uuid)
 
     @staticmethod
diff --git a/graphene/utils/annotate.py b/graphene/utils/annotate.py
index 43a26ef6..18dcd881 100644
--- a/graphene/utils/annotate.py
+++ b/graphene/utils/annotate.py
@@ -22,9 +22,12 @@ def annotate(_func=None, _trigger_warning=True, **annotations):
 
     # We make sure the annotations are valid
     for key, value in annotations.items():
-        assert key in func_signature.parameters, (
-            'The key {key} is not a function parameter in the function "{func_name}".'
-        ).format(key=key, func_name=func_name(_func))
+        if func_signature.parameters.get(key, None) is None:
+            raise AssertionError(
+                'The key {key} is not a function parameter in the function "{func_name}".'.format(
+                    key=key, func_name=func_name(_func)
+                )
+            )
 
     func_annotations = getattr(_func, "__annotations__", None)
     if func_annotations is None:
diff --git a/graphene/utils/comparison_helper.py b/graphene/utils/comparison_helper.py
new file mode 100644
index 00000000..c0dc8242
--- /dev/null
+++ b/graphene/utils/comparison_helper.py
@@ -0,0 +1,3 @@
+def raise_assertion_if(condition=None, message=None):
+    if condition:
+        raise AssertionError(message)
diff --git a/graphene/utils/subclass_with_meta.py b/graphene/utils/subclass_with_meta.py
index 01fc5375..2889862f 100644
--- a/graphene/utils/subclass_with_meta.py
+++ b/graphene/utils/subclass_with_meta.py
@@ -42,10 +42,15 @@ class SubclassWithMeta(six.with_metaclass(SubclassWithMeta_Meta)):
 
         abstract = options.pop("abstract", False)
         if abstract:
-            assert not options, (
-                "Abstract types can only contain the abstract attribute. "
-                "Received: abstract, {option_keys}"
-            ).format(option_keys=", ".join(options.keys()))
+            if options:
+                raise AssertionError(
+                    """
+                       Abstract types can only contain the abstract attribute.
+                       Received: abstract, {option_keys}
+                    """.format(
+                        option_keys=", ".join(options.keys())
+                    )
+                )
         else:
             super_class = super(cls, cls)
             if hasattr(super_class, "__init_subclass_with_meta__"):