diff --git a/graphene/types/uuid.py b/graphene/types/uuid.py
index abb8f110..b9687e1e 100644
--- a/graphene/types/uuid.py
+++ b/graphene/types/uuid.py
@@ -1,5 +1,5 @@
 from __future__ import absolute_import
-
+import six
 from uuid import UUID as _UUID
 
 from graphql.language import ast
@@ -12,8 +12,9 @@ class UUID(Scalar):
 
     @staticmethod
     def serialize(uuid):
-        if isinstance(uuid, str):
+        if isinstance(uuid, six.string_types):
             uuid = _UUID(uuid)
+
         assert isinstance(uuid, _UUID), "Expected UUID instance, received {}".format(
             uuid
         )