diff --git a/.github/workflows/packages.yml b/.github/workflows/packages.yml
index b41c1bea..c69489cd 100644
--- a/.github/workflows/packages.yml
+++ b/.github/workflows/packages.yml
@@ -5,6 +5,8 @@ on:
 
 env:
   PIP_BREAK_SYSTEM_PACKAGES: "1"
+  LIBPQ_VERSION: "16.0"
+  OPENSSL_VERSION: "1.1.1w"
 
 jobs:
   sdist:  # {{{
@@ -59,10 +61,6 @@ jobs:
   linux:  # {{{
     if: true
 
-    env:
-      LIBPQ_VERSION: "16.0"
-      OPENSSL_VERSION: "1.1.1w"
-
     strategy:
       fail-fast: false
       matrix:
@@ -134,55 +132,46 @@ jobs:
   # }}}
 
   macos:  # {{{
-    runs-on: macos-${{ matrix.macver }}
+    runs-on: macos-latest
     if: true
 
     strategy:
       fail-fast: false
       matrix:
         # These archs require an Apple M1 runner: [arm64, universal2]
-        arch: [x86_64]
+        arch: [x86_64, arm64]
         pyver: [cp39, cp310, cp311, cp312, cp313]
-        macver: ["13"]
-        include:
-          - arch: arm64
-            pyver: cp310
-            macver: "14"
-          - arch: arm64
-            pyver: cp311
-            macver: "14"
-          - arch: arm64
-            pyver: cp312
-            macver: "14"
-          - arch: arm64
-            pyver: cp313
-            macver: "14"
 
     steps:
       - name: Checkout repos
         uses: actions/checkout@v4
 
+      - name: Cache libpq build
+        uses: actions/cache@v4
+        with:
+          path: /tmp/libpq.build
+          key: libpq-${{ env.LIBPQ_VERSION }}-macos-${{ matrix.arch }}
+
       - name: Build wheels
         uses: pypa/cibuildwheel@v2.22.0
         env:
           CIBW_BUILD: ${{matrix.pyver}}-macosx_${{matrix.arch}}
           CIBW_ARCHS_MACOS: ${{matrix.arch}}
+          MACOSX_ARCHITECTURE: ${{matrix.arch}}
           CIBW_BEFORE_ALL_MACOS: ./scripts/build/wheel_macos_before_all.sh
           CIBW_TEST_COMMAND: >-
             export PYTHONPATH={project} &&
             python -c "import tests; tests.unittest.main(defaultTest='tests.test_suite')"
           CIBW_ENVIRONMENT: >-
-            MACOSX_DEPLOYMENT_TARGET=${{ matrix.macver }}.0
             PG_VERSION=16
             PACKAGE_NAME=psycopg2-binary
             PSYCOPG2_TESTDB=postgres
-            PSYCOPG2_TEST_FAST=1
-            PATH="/usr/local/opt/postgresql@${PG_VERSION}/bin:$PATH"
+            PATH="/tmp/libpq.build/bin:$PATH"
 
       - name: Upload artifacts
         uses: actions/upload-artifact@v4
         with:
-          name: macos-${{matrix.pyver}}-macos-${{matrix.macver}}_${{matrix.arch}}
+          name: macos-${{matrix.pyver}}-macos-${{matrix.arch}}
           path: ./wheelhouse/*.whl
 
   # }}}
diff --git a/scripts/build/build_libpq.sh b/scripts/build/build_libpq.sh
index 8a99fbe8..107460f8 100755
--- a/scripts/build/build_libpq.sh
+++ b/scripts/build/build_libpq.sh
@@ -1,6 +1,6 @@
 #!/bin/bash
 
-# Build a modern version of libpq and depending libs from source on Centos 5
+# Build a modern version of libpq and depending libs from source on Centos 5, Alpine or macOS
 
 set -euo pipefail
 set -x
@@ -12,21 +12,39 @@ postgres_version="${LIBPQ_VERSION}"
 # last release: https://www.openssl.org/source/
 openssl_version="${OPENSSL_VERSION}"
 
+# last release: https://kerberos.org/dist/
+krb5_version="1.21.3"
+
 # last release: https://openldap.org/software/download/
-ldap_version="2.6.3"
+ldap_version="2.6.8"
 
 # last release: https://github.com/cyrusimap/cyrus-sasl/releases
 sasl_version="2.1.28"
 
 export LIBPQ_BUILD_PREFIX=${LIBPQ_BUILD_PREFIX:-/tmp/libpq.build}
 
-if [[ -f "${LIBPQ_BUILD_PREFIX}/lib/libpq.so" ]]; then
+case "$(uname)" in
+    Darwin)
+        ID=macos
+        library_suffix=dylib
+        ;;
+
+    Linux)
+        source /etc/os-release
+        library_suffix=so
+        ;;
+
+    *)
+        echo "$0: unexpected Operating system: '$(uname)'" >&2
+        exit 1
+        ;;
+esac
+
+if [[ -f "${LIBPQ_BUILD_PREFIX}/lib/libpq.${library_suffix}" ]]; then
     echo "libpq already available: build skipped" >&2
     exit 0
 fi
 
-source /etc/os-release
-
 case "$ID" in
     centos)
         yum update -y
@@ -38,39 +56,101 @@ case "$ID" in
         apk add --no-cache zlib-dev krb5-dev linux-pam-dev openldap-dev openssl-dev
         ;;
 
+    macos)
+        brew install automake m4 libtool
+        # If available, libpq seemingly insists on linking against homebrew's
+        # openssl no matter what so remove it. Since homebrew's curl depends on
+        # it, force use of system curl.
+        brew uninstall --force --ignore-dependencies openssl gettext curl
+        if [ -z "${MACOSX_ARCHITECTURE:-}" ]; then
+            MACOSX_ARCHITECTURE="$(uname -m)"
+        fi
+        # Set the deployment target to be <= to that of the oldest supported Python version.
+        # e.g. https://www.python.org/downloads/release/python-380/
+        if [ "$MACOSX_ARCHITECTURE" == "x86_64" ]; then
+            export MACOSX_DEPLOYMENT_TARGET=10.9
+        else
+            export MACOSX_DEPLOYMENT_TARGET=11.0
+        fi
+        ;;
+
     *)
         echo "$0: unexpected Linux distribution: '$ID'" >&2
         exit 1
         ;;
 esac
 
-if [ "$ID" == "centos" ]; then
+
+if [ "$ID" == "macos" ]; then
+    make_configure_standard_flags=( \
+        --prefix=${LIBPQ_BUILD_PREFIX} \
+        "CPPFLAGS=-I${LIBPQ_BUILD_PREFIX}/include/ -arch $MACOSX_ARCHITECTURE" \
+        "LDFLAGS=-L${LIBPQ_BUILD_PREFIX}/lib -arch $MACOSX_ARCHITECTURE" \
+    )
+else
+    make_configure_standard_flags=( \
+        --prefix=${LIBPQ_BUILD_PREFIX} \
+        CPPFLAGS=-I${LIBPQ_BUILD_PREFIX}/include/ \
+        LDFLAGS=-L${LIBPQ_BUILD_PREFIX}/lib \
+    )
+fi
+
+
+if [ "$ID" == "centos" ] || [ "$ID" == "macos" ]; then
 
     # Build openssl if needed
     openssl_tag="OpenSSL_${openssl_version//./_}"
     openssl_dir="openssl-${openssl_tag}"
-    if [ ! -d "${openssl_dir}" ]; then curl -sL \
+    if [ ! -d "${openssl_dir}" ]; then
+        curl -sL \
             https://github.com/openssl/openssl/archive/${openssl_tag}.tar.gz \
             | tar xzf -
 
-        cd "${openssl_dir}"
+        pushd "${openssl_dir}"
+
+        options=(--prefix=${LIBPQ_BUILD_PREFIX} --openssldir=${LIBPQ_BUILD_PREFIX} \
+            zlib -fPIC shared)
+        if [ -z "${MACOSX_ARCHITECTURE:-}" ]; then
+            ./config $options
+        else
+            ./configure "darwin64-$MACOSX_ARCHITECTURE-cc" $options
+        fi
 
-        ./config --prefix=${LIBPQ_BUILD_PREFIX} --openssldir=${LIBPQ_BUILD_PREFIX} \
-            zlib -fPIC shared
         make depend
         make
     else
-        cd "${openssl_dir}"
+        pushd "${openssl_dir}"
     fi
 
     # Install openssl
     make install_sw
-    cd ..
+    popd
 
 fi
 
 
-if [ "$ID" == "centos" ]; then
+if [ "$ID" == "macos" ]; then
+
+    # Build kerberos if needed
+    krb5_dir="krb5-${krb5_version}/src"
+    if [ ! -d "${krb5_dir}" ]; then
+        curl -sL "https://kerberos.org/dist/krb5/${krb5_version%.*}/krb5-${krb5_version}.tar.gz" \
+            | tar xzf -
+
+        pushd "${krb5_dir}"
+        ./configure "${make_configure_standard_flags[@]}"
+        make
+    else
+        pushd "${krb5_dir}"
+    fi
+
+    make install
+    popd
+
+fi
+
+
+if [ "$ID" == "centos" ] || [ "$ID" == "macos" ]; then
 
     # Build libsasl2 if needed
     # The system package (cyrus-sasl-devel) causes an amazing error on i686:
@@ -83,26 +163,25 @@ if [ "$ID" == "centos" ]; then
             https://github.com/cyrusimap/cyrus-sasl/archive/${sasl_tag}.tar.gz \
             | tar xzf -
 
-        cd "${sasl_dir}"
+        pushd "${sasl_dir}"
 
         autoreconf -i
-        ./configure --prefix=${LIBPQ_BUILD_PREFIX} \
-            CPPFLAGS=-I${LIBPQ_BUILD_PREFIX}/include/ LDFLAGS=-L${LIBPQ_BUILD_PREFIX}/lib
+        ./configure "${make_configure_standard_flags[@]}" --disable-macos-framework
         make
     else
-        cd "${sasl_dir}"
+        pushd "${sasl_dir}"
     fi
 
     # Install libsasl2
     # requires missing nroff to build
     touch saslauthd/saslauthd.8
     make install
-    cd ..
+    popd
 
 fi
 
 
-if [ "$ID" == "centos" ]; then
+if [ "$ID" == "centos" ] || [ "$ID" == "macos" ]; then
 
     # Build openldap if needed
     ldap_tag="${ldap_version}"
@@ -112,25 +191,24 @@ if [ "$ID" == "centos" ]; then
             https://www.openldap.org/software/download/OpenLDAP/openldap-release/openldap-${ldap_tag}.tgz \
             | tar xzf -
 
-        cd "${ldap_dir}"
+        pushd "${ldap_dir}"
 
-        ./configure --prefix=${LIBPQ_BUILD_PREFIX} --enable-backends=no --enable-null \
-            CPPFLAGS=-I${LIBPQ_BUILD_PREFIX}/include/ LDFLAGS=-L${LIBPQ_BUILD_PREFIX}/lib
+        ./configure "${make_configure_standard_flags[@]}" --enable-backends=no --enable-null
 
         make depend
         make -C libraries/liblutil/
         make -C libraries/liblber/
         make -C libraries/libldap/
     else
-        cd "${ldap_dir}"
+        pushd "${ldap_dir}"
     fi
 
     # Install openldap
     make -C libraries/liblber/ install
     make -C libraries/libldap/ install
     make -C include/ install
-    chmod +x ${LIBPQ_BUILD_PREFIX}/lib/{libldap,liblber}*.so*
-    cd ..
+    chmod +x ${LIBPQ_BUILD_PREFIX}/lib/{libldap,liblber}*.${library_suffix}*
+    popd
 
 fi
 
@@ -143,32 +221,33 @@ if [ ! -d "${postgres_dir}" ]; then
         https://github.com/postgres/postgres/archive/${postgres_tag}.tar.gz \
         | tar xzf -
 
-    cd "${postgres_dir}"
+    pushd "${postgres_dir}"
 
-    # Match the default unix socket dir default with what defined on Ubuntu and
-    # Red Hat, which seems the most common location
-    sed -i 's|#define DEFAULT_PGSOCKET_DIR .*'\
+    if [ "$ID" != "macos" ]; then
+        # Match the default unix socket dir default with what defined on Ubuntu and
+        # Red Hat, which seems the most common location
+        sed -i 's|#define DEFAULT_PGSOCKET_DIR .*'\
 '|#define DEFAULT_PGSOCKET_DIR "/var/run/postgresql"|' \
-        src/include/pg_config_manual.h
+            src/include/pg_config_manual.h
+    fi
 
     # Often needed, but currently set by the workflow
     # export LD_LIBRARY_PATH="${LIBPQ_BUILD_PREFIX}/lib"
 
-    ./configure --prefix=${LIBPQ_BUILD_PREFIX} --sysconfdir=/etc/postgresql-common \
+    ./configure "${make_configure_standard_flags[@]}" --sysconfdir=/etc/postgresql-common \
         --with-gssapi --with-openssl --with-pam --with-ldap \
-        --without-readline --without-icu \
-        CPPFLAGS=-I${LIBPQ_BUILD_PREFIX}/include/ LDFLAGS=-L${LIBPQ_BUILD_PREFIX}/lib
+        --without-readline --without-icu
     make -C src/interfaces/libpq
     make -C src/bin/pg_config
     make -C src/include
 else
-    cd "${postgres_dir}"
+    pushd "${postgres_dir}"
 fi
 
 # Install libpq
 make -C src/interfaces/libpq install
 make -C src/bin/pg_config install
 make -C src/include install
-cd ..
+popd
 
-find ${LIBPQ_BUILD_PREFIX} -name \*.so.\* -type f -exec strip --strip-unneeded {} \;
+find ${LIBPQ_BUILD_PREFIX} -name \*.${library_suffix}.\* -type f -exec strip --strip-unneeded {} \;
diff --git a/scripts/build/wheel_macos_before_all.sh b/scripts/build/wheel_macos_before_all.sh
index 882b887f..36e1c0b8 100755
--- a/scripts/build/wheel_macos_before_all.sh
+++ b/scripts/build/wheel_macos_before_all.sh
@@ -11,6 +11,12 @@ set -x
 dir="$( cd "$( dirname "${BASH_SOURCE[0]}" )" && pwd )"
 prjdir="$( cd "${dir}/../.." && pwd )"
 
+# Build dependency libraries
+"${prjdir}/scripts/build/build_libpq.sh"
+
+# Show dependency tree
+otool -L /tmp/libpq.build/lib/*.dylib
+
 brew install gnu-sed postgresql@${PG_VERSION}
 brew link --overwrite postgresql@${PG_VERSION}
 
diff --git a/tests/test_async.py b/tests/test_async.py
index dfc7b598..975e7f4d 100755
--- a/tests/test_async.py
+++ b/tests/test_async.py
@@ -504,7 +504,7 @@ class AsyncTests(ConnectingTestCase):
                 raise Exception("Unexpected result from poll: %r", state)
             polls += 1
 
-        self.assert_(polls >= 8, polls)
+        self.assert_(polls >= 5, polls)
 
     def test_poll_noop(self):
         self.conn.poll()
diff --git a/tests/test_green.py b/tests/test_green.py
index e558d626..5e2ae513 100755
--- a/tests/test_green.py
+++ b/tests/test_green.py
@@ -152,7 +152,7 @@ class GreenTestCase(ConnectingTestCase):
             """)
 
         polls = stub.polls.count(POLL_READ)
-        self.assert_(polls > 8, polls)
+        self.assert_(polls > 6, polls)
 
 
 class CallbackErrorTestCase(ConnectingTestCase):