diff --git a/psycopg/_psycopg.vc9.amd64.manifest b/psycopg/_psycopg.vc9.amd64.manifest
new file mode 100644
index 00000000..e92d583f
--- /dev/null
+++ b/psycopg/_psycopg.vc9.amd64.manifest
@@ -0,0 +1,15 @@
+<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
+<assembly xmlns="urn:schemas-microsoft-com:asm.v1" manifestVersion="1.0">
+  <trustInfo xmlns="urn:schemas-microsoft-com:asm.v3">
+    <security>
+      <requestedPrivileges>
+        <requestedExecutionLevel level="asInvoker" uiAccess="false"></requestedExecutionLevel>
+      </requestedPrivileges>
+    </security>
+  </trustInfo>
+  <dependency>
+    <dependentAssembly>
+      <assemblyIdentity type="win32" name="Microsoft.VC90.CRT" version="9.0.21022.8" processorArchitecture="amd64" publicKeyToken="1fc8b3b9a1e18e3b"></assemblyIdentity>
+    </dependentAssembly>
+  </dependency>
+</assembly>
diff --git a/psycopg/_psycopg.vc9.manifest b/psycopg/_psycopg.vc9.x86.manifest
similarity index 73%
rename from psycopg/_psycopg.vc9.manifest
rename to psycopg/_psycopg.vc9.x86.manifest
index ebfb890b..9fc55da4 100644
--- a/psycopg/_psycopg.vc9.manifest
+++ b/psycopg/_psycopg.vc9.x86.manifest
@@ -9,7 +9,7 @@
   </trustInfo>
   <dependency>
     <dependentAssembly>
-      <assemblyIdentity type="win32" name="Microsoft.vc90.CRT" version="9.0.21022.8" processorArchitecture="*" publicKeyToken="1fc8b3b9a1e18e3b"></assemblyIdentity>
+      <assemblyIdentity type="win32" name="Microsoft.VC90.CRT" version="9.0.21022.8" processorArchitecture="x86" publicKeyToken="1fc8b3b9a1e18e3b"></assemblyIdentity>
     </dependentAssembly>
   </dependency>
 </assembly>
diff --git a/setup.py b/setup.py
index f5881e45..0640bc14 100644
--- a/setup.py
+++ b/setup.py
@@ -55,6 +55,7 @@ from distutils.command.build_ext import build_ext
 from distutils.sysconfig import get_python_inc
 from distutils.ccompiler import get_default_compiler
 from distutils.dep_util import newer_group
+from distutils.util import get_platform
 try:
     from distutils.command.build_py import build_py_2to3 as build_py
 except ImportError:
@@ -158,8 +159,13 @@ class psycopg_build_ext(build_ext):
         sysVer = sys.version_info[:2]
         if self.get_compiler().lower().startswith('msvc') and \
                 sysVer in ((2,6), (2,7)):
+            platform = get_platform()
+            # Default to the x86 manifest
+            manifest = '_psycopg.vc9.x86.manifest'
+            if platform == 'win-amd64':
+                manifest = '_psycopg.vc9.amd64.manifest'
             self.compiler.spawn(['mt.exe', '-nologo', '-manifest',
-                os.path.join('psycopg', '_psycopg.vc9.manifest'),
+                os.path.join('psycopg', manifest),
                 '-outputresource:%s;2' % (os.path.join(self.build_lib, 'psycopg2', '_psycopg.pyd'))])
 
     def finalize_win32(self):