Compiling and installing psycopg ******************************** While psycopg 1.x used autoconf for its build process psycopg 2 switched to the more pythoning setup.py. Currently both psycopg's author and distutils have some limitations so the file setup.cfg is almost unused and most build options are hidden in setup.py. Before building psycopg look at the very first lines of setup.py and change any settings to follow your system (or taste); then: python setup.py build to build in the local directory; and: python setup.py install to install system-wide.