diff --git a/.github/workflows/wheels-dependencies.sh b/.github/workflows/wheels-dependencies.sh
index 58621bca1..2eac4d3d7 100755
--- a/.github/workflows/wheels-dependencies.sh
+++ b/.github/workflows/wheels-dependencies.sh
@@ -72,6 +72,14 @@ function build_zlib_ng {
         && ./configure --prefix=$BUILD_PREFIX --zlib-compat \
         && make -j4 \
         && make install)
+
+    if [ -n "$IS_MACOS" ]; then
+        # Ensure that on macOS, the library name is an absolute path, not an
+        # @rpath, so that delocate picks up the right library (and doesn't need
+        # DYLD_LIBRARY_PATH to be set). The default Makefile doesn't have an
+        # option to control the install_name.
+        install_name_tool -id $BUILD_PREFIX/lib/libz.1.dylib $BUILD_PREFIX/lib/libz.1.dylib
+    fi
     touch zlib-stamp
 }
 
diff --git a/pyproject.toml b/pyproject.toml
index 2c6c7bcd0..aaaba0032 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -104,7 +104,6 @@ test-extras = "tests"
 
 [tool.cibuildwheel.macos.environment]
 PATH = "$(pwd)/build/deps/darwin/bin:$(dirname $(which python3)):/usr/bin:/bin:/usr/sbin:/sbin:/Library/Apple/usr/bin"
-DYLD_LIBRARY_PATH = "$(pwd)/build/deps/darwin/lib"
 
 [tool.black]
 exclude = "wheels/multibuild"