diff --git a/Tests/images/hopper_unknown_pixel_mode.tif b/Tests/images/hopper_unknown_pixel_mode.tif
new file mode 100644
index 000000000..89a8c5e17
Binary files /dev/null and b/Tests/images/hopper_unknown_pixel_mode.tif differ
diff --git a/Tests/test_file_tiff.py b/Tests/test_file_tiff.py
index 95a181363..4a0bfea58 100644
--- a/Tests/test_file_tiff.py
+++ b/Tests/test_file_tiff.py
@@ -220,6 +220,10 @@ class TestFileTiff(PillowTestCase):
         self.assertEqual(
             im.getextrema(), (-3.140936851501465, 3.140684127807617))
 
+    def test_unknown_pixel_mode(self):
+        self.assertRaises(
+            IOError, Image.open, 'Tests/images/hopper_unknown_pixel_mode.tif')
+
     def test_n_frames(self):
         for path, n_frames in [
             ['Tests/images/multipage-lastframe.tif', 1],
diff --git a/src/PIL/DcxImagePlugin.py b/src/PIL/DcxImagePlugin.py
index 1b72cbc99..34a413dd7 100644
--- a/src/PIL/DcxImagePlugin.py
+++ b/src/PIL/DcxImagePlugin.py
@@ -83,7 +83,8 @@ class DcxImageFile(PcxImageFile):
 
     def _close__fp(self):
         try:
-            self.__fp.close()
+            if self.__fp != self.fp:
+                self.__fp.close()
         except AttributeError:
             pass
         finally:
diff --git a/src/PIL/FliImagePlugin.py b/src/PIL/FliImagePlugin.py
index 1c8232fba..4c3f533f7 100644
--- a/src/PIL/FliImagePlugin.py
+++ b/src/PIL/FliImagePlugin.py
@@ -159,7 +159,8 @@ class FliImageFile(ImageFile.ImageFile):
 
     def _close__fp(self):
         try:
-            self.__fp.close()
+            if self.__fp != self.fp:
+                self.__fp.close()
         except AttributeError:
             pass
         finally:
diff --git a/src/PIL/GifImagePlugin.py b/src/PIL/GifImagePlugin.py
index 50b786a37..21fdcc476 100644
--- a/src/PIL/GifImagePlugin.py
+++ b/src/PIL/GifImagePlugin.py
@@ -304,7 +304,8 @@ class GifImageFile(ImageFile.ImageFile):
 
     def _close__fp(self):
         try:
-            self.__fp.close()
+            if self.__fp != self.fp:
+                self.__fp.close()
         except AttributeError:
             pass
         finally:
diff --git a/src/PIL/ImImagePlugin.py b/src/PIL/ImImagePlugin.py
index 1a4fdb65a..3ef6bed63 100644
--- a/src/PIL/ImImagePlugin.py
+++ b/src/PIL/ImImagePlugin.py
@@ -292,7 +292,8 @@ class ImImageFile(ImageFile.ImageFile):
 
     def _close__fp(self):
         try:
-            self.__fp.close()
+            if self.__fp != self.fp:
+                self.__fp.close()
         except AttributeError:
             pass
         finally:
diff --git a/src/PIL/Image.py b/src/PIL/Image.py
index 092cc8040..5c1b2a2a7 100644
--- a/src/PIL/Image.py
+++ b/src/PIL/Image.py
@@ -594,10 +594,10 @@ class Image(object):
         :ref:`file-handling` for more information.
         """
         try:
-            self.fp.close()
-            self.fp = None
             if hasattr(self, "_close__fp"):
                 self._close__fp()
+            self.fp.close()
+            self.fp = None
         except Exception as msg:
             logger.debug("Error closing: %s", msg)
 
@@ -611,12 +611,12 @@ class Image(object):
 
     if sys.version_info.major >= 3:
         def __del__(self):
+            if hasattr(self, "_close__fp"):
+                self._close__fp()
             if (hasattr(self, 'fp') and hasattr(self, '_exclusive_fp')
                and self.fp and self._exclusive_fp):
                 self.fp.close()
             self.fp = None
-            if hasattr(self, "_close__fp"):
-                self._close__fp()
 
     def _copy(self):
         self.load()
diff --git a/src/PIL/MicImagePlugin.py b/src/PIL/MicImagePlugin.py
index 6e29e456d..cff84d5eb 100644
--- a/src/PIL/MicImagePlugin.py
+++ b/src/PIL/MicImagePlugin.py
@@ -99,7 +99,8 @@ class MicImageFile(TiffImagePlugin.TiffImageFile):
 
     def _close__fp(self):
         try:
-            self.__fp.close()
+            if self.__fp != self.fp:
+                self.__fp.close()
         except AttributeError:
             pass
         finally:
diff --git a/src/PIL/MpoImagePlugin.py b/src/PIL/MpoImagePlugin.py
index 06b93d921..7afa3f35a 100644
--- a/src/PIL/MpoImagePlugin.py
+++ b/src/PIL/MpoImagePlugin.py
@@ -86,7 +86,8 @@ class MpoImageFile(JpegImagePlugin.JpegImageFile):
 
     def _close__fp(self):
         try:
-            self.__fp.close()
+            if self.__fp != self.fp:
+                self.__fp.close()
         except AttributeError:
             pass
         finally:
diff --git a/src/PIL/SpiderImagePlugin.py b/src/PIL/SpiderImagePlugin.py
index dcde2f395..4d5aa3f0e 100644
--- a/src/PIL/SpiderImagePlugin.py
+++ b/src/PIL/SpiderImagePlugin.py
@@ -195,7 +195,8 @@ class SpiderImageFile(ImageFile.ImageFile):
 
     def _close__fp(self):
         try:
-            self.__fp.close()
+            if self.__fp != self.fp:
+                self.__fp.close()
         except AttributeError:
             pass
         finally:
diff --git a/src/PIL/TiffImagePlugin.py b/src/PIL/TiffImagePlugin.py
index be24624d6..a39591937 100644
--- a/src/PIL/TiffImagePlugin.py
+++ b/src/PIL/TiffImagePlugin.py
@@ -1361,7 +1361,8 @@ class TiffImageFile(ImageFile.ImageFile):
 
     def _close__fp(self):
         try:
-            self.__fp.close()
+            if self.__fp != self.fp:
+                self.__fp.close()
         except AttributeError:
             pass
         finally: