diff --git a/Tests/test_imageqt.py b/Tests/test_imageqt.py
index 2ded37c09..bd93828ef 100644
--- a/Tests/test_imageqt.py
+++ b/Tests/test_imageqt.py
@@ -1,7 +1,16 @@
 from .helper import PillowTestCase, hopper
 
-from PIL import ImageQt
+import warnings
 
+deprecated = False
+with warnings.catch_warnings():
+    warnings.filterwarnings("error", category=DeprecationWarning)
+    try:
+        from PIL import ImageQt
+    except DeprecationWarning:
+        deprecated = True
+        warnings.filterwarnings("ignore", category=DeprecationWarning)
+        from PIL import ImageQt
 
 if ImageQt.qt_is_installed:
     from PIL.ImageQt import qRgba
@@ -78,3 +87,6 @@ class TestImageQt(PillowQtTestCase, PillowTestCase):
     def test_image(self):
         for mode in ('1', 'RGB', 'RGBA', 'L', 'P'):
             ImageQt.ImageQt(hopper(mode))
+
+    def test_deprecated(self):
+        self.assertEqual(ImageQt.qt_version in ["4", "side"], deprecated)
diff --git a/docs/deprecations.rst b/docs/deprecations.rst
index b8131ac05..bc4e83161 100644
--- a/docs/deprecations.rst
+++ b/docs/deprecations.rst
@@ -12,6 +12,17 @@ Deprecated features
 Below are features which are considered deprecated. Where appropriate,
 a ``DeprecationWarning`` is issued.
 
+PyQt4 and PySide
+~~~~~~~~~~~~~~~~
+
+.. deprecated:: 6.0.0
+
+Qt 4 reached end-of-life on 2015-12-19. Its Python bindings are also EOL: PyQt4 since
+2018-08-31 and PySide since 2015-10-14.
+
+Support for PyQt4 and PySide has been deprecated from ``ImageQt`` and will be removed in
+a future version. Please upgrade to PyQt5 or PySide2.
+
 PIL.*ImagePlugin.__version__ attributes
 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
diff --git a/docs/reference/ImageQt.rst b/docs/reference/ImageQt.rst
index 386401075..5128f28fb 100644
--- a/docs/reference/ImageQt.rst
+++ b/docs/reference/ImageQt.rst
@@ -7,6 +7,12 @@
 The :py:mod:`ImageQt` module contains support for creating PyQt4, PyQt5, PySide or
 PySide2 QImage objects from PIL images.
 
+Qt 4 reached end-of-life on 2015-12-19. Its Python bindings are also EOL: PyQt4 since
+2018-08-31 and PySide since 2015-10-14.
+
+Support for PyQt4 and PySide is deprecated since Pillow 6.0.0 and will be removed in a
+future version. Please upgrade to PyQt5 or PySide2.
+
 .. versionadded:: 1.1.6
 
 .. py:class:: ImageQt.ImageQt(image)
diff --git a/docs/releasenotes/6.0.0.rst b/docs/releasenotes/6.0.0.rst
index e1fa83cce..9fbb3d69a 100644
--- a/docs/releasenotes/6.0.0.rst
+++ b/docs/releasenotes/6.0.0.rst
@@ -32,6 +32,18 @@ API Changes
 Deprecations
 ^^^^^^^^^^^^
 
+PyQt4 and PySide
+~~~~~~~~~~~~~~~~
+
+Qt 4 reached end-of-life on 2015-12-19. Its Python bindings are also EOL: PyQt4 since
+2018-08-31 and PySide since 2015-10-14.
+
+Support for PyQt4 and PySide has been deprecated from ``ImageQt`` and will be removed in
+a future version. Please upgrade to PyQt5 or PySide2.
+
+PIL.*ImagePlugin.__version__ attributes
+~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+
 These version constants have been deprecated and will be removed in a future
 version.
 
diff --git a/src/PIL/ImageQt.py b/src/PIL/ImageQt.py
index b747781c5..02ce6354e 100644
--- a/src/PIL/ImageQt.py
+++ b/src/PIL/ImageQt.py
@@ -20,6 +20,7 @@ from . import Image
 from ._util import isPath, py3
 from io import BytesIO
 import sys
+import warnings
 
 qt_versions = [
     ['5', 'PyQt5'],
@@ -27,6 +28,12 @@ qt_versions = [
     ['4', 'PyQt4'],
     ['side', 'PySide']
 ]
+
+WARNING_TEXT = (
+    "Support for EOL {} is deprecated and will be removed in a future version. "
+    "Please upgrade to PyQt5 or PySide2."
+)
+
 # If a version has already been imported, attempt it first
 qt_versions.sort(key=lambda qt_version: qt_version[1] in sys.modules,
                  reverse=True)
@@ -41,9 +48,13 @@ for qt_version, qt_module in qt_versions:
         elif qt_module == 'PyQt4':
             from PyQt4.QtGui import QImage, qRgba, QPixmap
             from PyQt4.QtCore import QBuffer, QIODevice
+
+            warnings.warn(WARNING_TEXT.format(qt_module), DeprecationWarning)
         elif qt_module == 'PySide':
             from PySide.QtGui import QImage, qRgba, QPixmap
             from PySide.QtCore import QBuffer, QIODevice
+
+            warnings.warn(WARNING_TEXT.format(qt_module), DeprecationWarning)
     except (ImportError, RuntimeError):
         continue
     qt_is_installed = True
@@ -67,7 +78,7 @@ def fromqimage(im):
     """
     buffer = QBuffer()
     buffer.open(QIODevice.ReadWrite)
-    # preserve alha channel with png
+    # preserve alpha channel with png
     # otherwise ppm is more friendly with Image.open
     if im.hasAlphaChannel():
         im.save(buffer, 'png')