diff --git a/.github/workflows/wheels-dependencies.sh b/.github/workflows/wheels-dependencies.sh
index 142a91a3d..67933fe06 100755
--- a/.github/workflows/wheels-dependencies.sh
+++ b/.github/workflows/wheels-dependencies.sh
@@ -136,7 +136,6 @@ function build_libavif {
             -DCMAKE_INSTALL_PREFIX=$BUILD_PREFIX \
             -DCMAKE_INSTALL_LIBDIR=$BUILD_PREFIX/lib \
             -DCMAKE_INSTALL_NAME_DIR=$BUILD_PREFIX/lib \
-            -DCMAKE_MACOSX_RPATH=OFF \
             -DBUILD_SHARED_LIBS=ON \
             -DAVIF_LIBSHARPYUV=LOCAL \
             -DAVIF_LIBYUV=LOCAL \