diff --git a/Tests/images/rgb32rle_bottom_right.tga b/Tests/images/rgb32rle_bottom_right.tga
new file mode 100644
index 000000000..bd4609e9c
Binary files /dev/null and b/Tests/images/rgb32rle_bottom_right.tga differ
diff --git a/Tests/images/rgb32rle_top_right.tga b/Tests/images/rgb32rle_top_right.tga
new file mode 100644
index 000000000..78f9dc5df
Binary files /dev/null and b/Tests/images/rgb32rle_top_right.tga differ
diff --git a/Tests/test_file_tga.py b/Tests/test_file_tga.py
index 3450c9274..e2351d723 100644
--- a/Tests/test_file_tga.py
+++ b/Tests/test_file_tga.py
@@ -171,6 +171,15 @@ def test_save_orientation(tmp_path):
         assert test_im.info["orientation"] == 1
 
 
+def test_horizontal_orientations():
+    # These images have been manually hexedited to have the relevant orientations
+    with Image.open("Tests/images/rgb32rle_top_right.tga") as im:
+        assert im.load()[90, 90][:3] == (0, 0, 0)
+
+    with Image.open("Tests/images/rgb32rle_bottom_right.tga") as im:
+        assert im.load()[90, 90][:3] == (0, 255, 0)
+
+
 def test_save_rle(tmp_path):
     test_file = "Tests/images/rgb32rle.tga"
     with Image.open(test_file) as im:
diff --git a/src/PIL/TgaImagePlugin.py b/src/PIL/TgaImagePlugin.py
index 5e5d52d1a..ed63da95f 100644
--- a/src/PIL/TgaImagePlugin.py
+++ b/src/PIL/TgaImagePlugin.py
@@ -93,9 +93,10 @@ class TgaImageFile(ImageFile.ImageFile):
 
         # orientation
         orientation = flags & 0x30
-        if orientation == 0x20:
+        self._flip_horizontally = orientation in [0x10, 0x30]
+        if orientation in [0x20, 0x30]:
             orientation = 1
-        elif not orientation:
+        elif orientation in [0, 0x10]:
             orientation = -1
         else:
             raise SyntaxError("unknown TGA orientation")
@@ -149,6 +150,10 @@ class TgaImageFile(ImageFile.ImageFile):
         except KeyError:
             pass  # cannot decode
 
+    def load_end(self):
+        if self._flip_horizontally:
+            self.im = self.im.transpose(Image.FLIP_LEFT_RIGHT)
+
 
 #
 # --------------------------------------------------------------------