diff --git a/Makefile b/Makefile
index 477d92609..1f9b4a370 100644
--- a/Makefile
+++ b/Makefile
@@ -2,7 +2,6 @@
 
 .PHONY: clean
 clean:
-	python3 setup.py clean
 	rm src/PIL/*.so || true
 	rm -r build || true
 	find . -name __pycache__ | xargs rm -r || true