diff --git a/Tests/helper.py b/Tests/helper.py
index 8fb34848b..030335745 100644
--- a/Tests/helper.py
+++ b/Tests/helper.py
@@ -187,10 +187,10 @@ class PillowTestCase(unittest.TestCase):
         return result
 
     def assert_all_same(self, items, msg=None):
-        self.assertTrue(items.count(items[0]) == len(items), msg)
+        self.assertEqual(items.count(items[0]), len(items), msg)
 
     def assert_not_all_same(self, items, msg=None):
-        self.assertFalse(items.count(items[0]) == len(items), msg)
+        self.assertNotEqual(items.count(items[0]), len(items), msg)
 
     def assert_tuple_approx_equal(self, actuals, targets, threshold, msg):
         """Tests if actuals has values within threshold from targets"""
diff --git a/Tests/test_file_libtiff.py b/Tests/test_file_libtiff.py
index ddd39ba8c..5b0b0c46b 100644
--- a/Tests/test_file_libtiff.py
+++ b/Tests/test_file_libtiff.py
@@ -545,11 +545,11 @@ class TestFileLibTiff(LibTiffTestCase):
     def test_read_icc(self):
         with Image.open("Tests/images/hopper.iccprofile.tif") as img:
             icc = img.info.get('icc_profile')
-            self.assertNotEqual(icc, None)
+            self.assertIsNotNone(icc)
         TiffImagePlugin.READ_LIBTIFF = True
         with Image.open("Tests/images/hopper.iccprofile.tif") as img:
             icc_libtiff = img.info.get('icc_profile')
-            self.assertNotEqual(icc_libtiff, None)
+            self.assertIsNotNone(icc_libtiff)
         TiffImagePlugin.READ_LIBTIFF = False
         self.assertEqual(icc, icc_libtiff)
 
diff --git a/Tests/test_image.py b/Tests/test_image.py
index ad56a079a..715c588da 100644
--- a/Tests/test_image.py
+++ b/Tests/test_image.py
@@ -516,7 +516,7 @@ class TestImage(PillowTestCase):
                 self.assertEqual(new_im.palette.tobytes(),
                                  palette_result.tobytes())
             else:
-                self.assertEqual(new_im.palette, None)
+                self.assertIsNone(new_im.palette)
 
         _make_new(im, im_p, im_p.palette)
         _make_new(im_p, im, None)
diff --git a/Tests/test_image_convert.py b/Tests/test_image_convert.py
index 1b3815d80..e57ae4305 100644
--- a/Tests/test_image_convert.py
+++ b/Tests/test_image_convert.py
@@ -88,7 +88,7 @@ class TestImageConvert(PillowTestCase):
         # Assert
         self.assertNotIn('transparency', im_rgba.info)
         # https://github.com/python-pillow/Pillow/issues/2702
-        self.assertEqual(im_rgba.palette, None)
+        self.assertIsNone(im_rgba.palette)
 
     def test_trns_l(self):
         im = hopper('L')