diff --git a/Tests/images/2422.flc b/Tests/images/2422.flc
new file mode 100644
index 000000000..eed5fb59e
Binary files /dev/null and b/Tests/images/2422.flc differ
diff --git a/Tests/test_file_fli.py b/Tests/test_file_fli.py
index fc524721c..f86fb8d09 100644
--- a/Tests/test_file_fli.py
+++ b/Tests/test_file_fli.py
@@ -4,7 +4,7 @@ import warnings
 
 import pytest
 
-from PIL import FliImagePlugin, Image
+from PIL import FliImagePlugin, Image, ImageFile
 
 from .helper import assert_image_equal, assert_image_equal_tofile, is_pypy
 
@@ -12,9 +12,12 @@ from .helper import assert_image_equal, assert_image_equal_tofile, is_pypy
 # save as...-> hopper.fli, default options.
 static_test_file = "Tests/images/hopper.fli"
 
-# From https://samples.libav.org/fli-flc/
+# From https://samples.ffmpeg.org/fli-flc/
 animated_test_file = "Tests/images/a.fli"
 
+# From https://samples.ffmpeg.org/fli-flc/
+animated_test_file_with_prefix_chunk = "Tests/images/2422.flc"
+
 
 def test_sanity() -> None:
     with Image.open(static_test_file) as im:
@@ -32,6 +35,24 @@ def test_sanity() -> None:
         assert im.is_animated
 
 
+def test_prefix_chunk() -> None:
+    ImageFile.LOAD_TRUNCATED_IMAGES = True
+    try:
+        with Image.open(animated_test_file_with_prefix_chunk) as im:
+            assert im.mode == "P"
+            assert im.size == (320, 200)
+            assert im.format == "FLI"
+            assert im.info["duration"] == 171
+            assert im.is_animated
+
+            palette = im.getpalette()
+            assert palette[3:6] == [255, 255, 255]
+            assert palette[381:384] == [204, 204, 12]
+            assert palette[765:] == [252, 0, 0]
+    finally:
+        ImageFile.LOAD_TRUNCATED_IMAGES = False
+
+
 @pytest.mark.skipif(is_pypy(), reason="Requires CPython")
 def test_unclosed_file() -> None:
     def open() -> None:
diff --git a/src/PIL/FliImagePlugin.py b/src/PIL/FliImagePlugin.py
index 9769761fc..f9e4c731c 100644
--- a/src/PIL/FliImagePlugin.py
+++ b/src/PIL/FliImagePlugin.py
@@ -77,6 +77,7 @@ class FliImageFile(ImageFile.ImageFile):
         if i16(s, 4) == 0xF100:
             # prefix chunk; ignore it
             self.__offset = self.__offset + i32(s)
+            self.fp.seek(self.__offset)
             s = self.fp.read(16)
 
         if i16(s, 4) == 0xF1FA: