diff --git a/.azure-pipelines/jobs/lint.yml b/.azure-pipelines/jobs/lint.yml
new file mode 100644
index 000000000..d017590f8
--- /dev/null
+++ b/.azure-pipelines/jobs/lint.yml
@@ -0,0 +1,28 @@
+parameters:
+  name: ''  # defaults for any parameters that aren't specified
+  vmImage: ''
+
+jobs:
+
+- job:  ${{ parameters.name }}
+  pool:
+    vmImage: ${{ parameters.vmImage }}
+
+  strategy:
+    matrix:
+      Python37:
+        python.version: '3.7'
+
+  steps:
+  - task: UsePythonVersion@0
+    inputs:
+      versionSpec: '$(python.version)'
+      architecture: 'x64'
+
+  - script: |
+      python -m pip install --upgrade tox
+    displayName: 'Install dependencies'
+
+  - script: |
+      tox -e lint
+    displayName: 'Lint'
diff --git a/.azure-pipelines/jobs/test-docker.yml b/.azure-pipelines/jobs/test-docker.yml
new file mode 100644
index 000000000..41dc2daec
--- /dev/null
+++ b/.azure-pipelines/jobs/test-docker.yml
@@ -0,0 +1,22 @@
+parameters:
+  docker: ''  # defaults for any parameters that aren't specified
+  dockerTag: 'master'
+  name: ''
+  vmImage: 'Ubuntu-16.04'
+
+jobs:
+
+- job:  ${{ parameters.name }}
+  pool:
+    vmImage: ${{ parameters.vmImage }}
+
+  steps:
+  - script: |
+      docker pull pythonpillow/${{ parameters.docker }}:${{ parameters.dockerTag }}
+    displayName: 'Docker pull'
+
+  - script: |
+      # The Pillow user in the docker container is UID 1000
+      sudo chown -R 1000 $(Build.SourcesDirectory)
+      docker run -v $(Build.SourcesDirectory):/Pillow pythonpillow/${{ parameters.docker }}:${{ parameters.dockerTag }}
+    displayName: 'Docker build'
diff --git a/CHANGES.rst b/CHANGES.rst
index e1c08d8bd..01fc87bf7 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -5,6 +5,39 @@ Changelog (Pillow)
 6.0.0 (unreleased)
 ------------------
 
+- Python 2.7 support will be removed in Pillow 7.0.0 #3682
+  [hugovk]
+
+- Removed deprecated VERSION #3624
+  [hugovk]
+
+- Fix 'BytesWarning: Comparison between bytes and string' in PdfDict #3580
+  [jdufresne]
+
+- Do not resize in Image.thumbnail if already the destination size #3632
+  [radarhere]
+
+- Replace .seek() magic numbers with io.SEEK_* constants #3572
+  [jdufresne]
+
+- Make ContainerIO.isatty() return a bool, not int #3568
+  [jdufresne]
+
+- Add support for I;16 modes for more transpose operations #3563
+  [radarhere]
+
+- Deprecate support for PyQt4 and PySide #3655
+  [hugovk, radarhere]
+
+- Add TIFF compression codecs: LZMA, Zstd, WebP #3555
+  [cgohlke]
+
+- Fixed pickling of iTXt class with protocol > 1 #3537
+  [radarhere]
+
+- _util.isPath returns True for pathlib.Path objects #3616
+  [wbadart]
+
 - Remove unnecessary unittest.main() boilerplate from test files #3631
   [jdufresne]
 
diff --git a/MANIFEST.in b/MANIFEST.in
index 809d0d667..f11ee174c 100644
--- a/MANIFEST.in
+++ b/MANIFEST.in
@@ -23,9 +23,10 @@ exclude .codecov.yml
 exclude .editorconfig
 exclude .landscape.yaml
 exclude .readthedocs.yml
-exclude .travis
-exclude .travis/*
+exclude azure-pipelines.yml
 exclude tox.ini
 global-exclude .git*
 global-exclude *.pyc
 global-exclude *.so
+prune .azure-pipelines
+prune .travis
diff --git a/RELEASING.md b/RELEASING.md
index 40a48c4d3..f28e5f134 100644
--- a/RELEASING.md
+++ b/RELEASING.md
@@ -88,14 +88,7 @@ Released as needed privately to individual vendors for critical security-related
   ```bash
   git clone https://github.com/python-pillow/pillow-wheels
   cd pillow-wheels
-  git submodule init
-  git submodule update Pillow
-  cd Pillow
-  git fetch --all
-  git checkout [[release tag]]
-  cd ..
-  git commit -m "Pillow -> 5.2.0" Pillow
-  git push
+  ./update-pillow-tag.sh [[release tag]]
   ```
 * [ ] Download distributions from the [Pillow Wheel Builder container](http://a365fff413fe338398b6-1c8a9b3114517dc5fe17b7c3f8c63a43.r19.cf2.rackcdn.com/).
   ```bash
diff --git a/Tests/images/itxt_chunks.png b/Tests/images/itxt_chunks.png
new file mode 100644
index 000000000..ca098440c
Binary files /dev/null and b/Tests/images/itxt_chunks.png differ
diff --git a/Tests/test_000_sanity.py b/Tests/test_000_sanity.py
index 321a6b3ce..b9dd413f9 100644
--- a/Tests/test_000_sanity.py
+++ b/Tests/test_000_sanity.py
@@ -11,8 +11,6 @@ class TestSanity(PillowTestCase):
         # Make sure we have the binary extension
         PIL.Image.core.new("L", (100, 100))
 
-        self.assertEqual(PIL.Image.VERSION[:3], '1.1')
-
         # Create an image and do stuff with it.
         im = PIL.Image.new("1", (100, 100))
         self.assertEqual((im.mode, im.size), ('1', (100, 100)))
diff --git a/Tests/test_file_container.py b/Tests/test_file_container.py
index 8ca3310e5..04f055464 100644
--- a/Tests/test_file_container.py
+++ b/Tests/test_file_container.py
@@ -16,7 +16,7 @@ class TestFileContainer(PillowTestCase):
         im = hopper()
         container = ContainerIO.ContainerIO(im, 0, 0)
 
-        self.assertEqual(container.isatty(), 0)
+        self.assertFalse(container.isatty())
 
     def test_seek_mode_0(self):
         # Arrange
diff --git a/Tests/test_file_msp.py b/Tests/test_file_msp.py
index 66af65fcd..724fc78b1 100644
--- a/Tests/test_file_msp.py
+++ b/Tests/test_file_msp.py
@@ -12,11 +12,11 @@ YA_EXTRA_DIR = "Tests/images/msp"
 class TestFileMsp(PillowTestCase):
 
     def test_sanity(self):
-        file = self.tempfile("temp.msp")
+        test_file = self.tempfile("temp.msp")
 
-        hopper("1").save(file)
+        hopper("1").save(test_file)
 
-        im = Image.open(file)
+        im = Image.open(test_file)
         im.load()
         self.assertEqual(im.mode, "1")
         self.assertEqual(im.size, (128, 128))
diff --git a/Tests/test_file_ppm.py b/Tests/test_file_ppm.py
index 47f8b845e..dc239cc4c 100644
--- a/Tests/test_file_ppm.py
+++ b/Tests/test_file_ppm.py
@@ -14,12 +14,14 @@ class TestFilePpm(PillowTestCase):
         self.assertEqual(im.mode, "RGB")
         self.assertEqual(im.size, (128, 128))
         self.assertEqual(im.format, "PPM")
+        self.assertEqual(im.get_format_mimetype(), "image/x-portable-pixmap")
 
     def test_16bit_pgm(self):
         im = Image.open('Tests/images/16_bit_binary.pgm')
         im.load()
         self.assertEqual(im.mode, 'I')
         self.assertEqual(im.size, (20, 100))
+        self.assertEqual(im.get_format_mimetype(), "image/x-portable-graymap")
 
         tgt = Image.open('Tests/images/16_bit_binary_pgm.png')
         self.assert_image_equal(im, tgt)
@@ -49,3 +51,16 @@ class TestFilePpm(PillowTestCase):
 
         with self.assertRaises(IOError):
             Image.open('Tests/images/negative_size.ppm')
+
+    def test_mimetypes(self):
+        path = self.tempfile('temp.pgm')
+
+        with open(path, 'w') as f:
+            f.write("P4\n128 128\n255")
+        im = Image.open(path)
+        self.assertEqual(im.get_format_mimetype(), "image/x-portable-bitmap")
+
+        with open(path, 'w') as f:
+            f.write("PyCMYK\n128 128\n255")
+        im = Image.open(path)
+        self.assertEqual(im.get_format_mimetype(), "image/x-portable-anymap")
diff --git a/Tests/test_image_thumbnail.py b/Tests/test_image_thumbnail.py
index d03ea4141..fbadf50cf 100644
--- a/Tests/test_image_thumbnail.py
+++ b/Tests/test_image_thumbnail.py
@@ -1,4 +1,5 @@
 from .helper import PillowTestCase, hopper
+from PIL import Image
 
 
 class TestImageThumbnail(PillowTestCase):
@@ -35,3 +36,14 @@ class TestImageThumbnail(PillowTestCase):
         im = hopper().resize((128, 128))
         im.thumbnail((100, 100))
         self.assert_image(im, im.mode, (100, 100))
+
+    def test_no_resize(self):
+        # Check that draft() can resize the image to the destination size
+        im = Image.open("Tests/images/hopper.jpg")
+        im.draft(None, (64, 64))
+        self.assertEqual(im.size, (64, 64))
+
+        # Test thumbnail(), where only draft() is necessary to resize the image
+        im = Image.open("Tests/images/hopper.jpg")
+        im.thumbnail((64, 64))
+        self.assert_image(im, im.mode, (64, 64))
diff --git a/Tests/test_image_transpose.py b/Tests/test_image_transpose.py
index 8ffb9e9bf..ad8c77126 100644
--- a/Tests/test_image_transpose.py
+++ b/Tests/test_image_transpose.py
@@ -7,10 +7,9 @@ from PIL.Image import (FLIP_LEFT_RIGHT, FLIP_TOP_BOTTOM, ROTATE_90, ROTATE_180,
 
 class TestImageTranspose(PillowTestCase):
 
-    hopper = {
-        'L': helper.hopper('L').crop((0, 0, 121, 127)).copy(),
-        'RGB': helper.hopper('RGB').crop((0, 0, 121, 127)).copy(),
-    }
+    hopper = {mode: helper.hopper(mode).crop((0, 0, 121, 127)).copy() for mode in [
+        'L', 'RGB', 'I;16', 'I;16L', 'I;16B'
+    ]}
 
     def test_flip_left_right(self):
         def transpose(mode):
@@ -25,7 +24,7 @@ class TestImageTranspose(PillowTestCase):
             self.assertEqual(im.getpixel((1, y-2)), out.getpixel((x-2, y-2)))
             self.assertEqual(im.getpixel((x-2, y-2)), out.getpixel((1, y-2)))
 
-        for mode in ("L", "RGB"):
+        for mode in ("L", "RGB", "I;16", "I;16L", "I;16B"):
             transpose(mode)
 
     def test_flip_top_bottom(self):
@@ -41,7 +40,7 @@ class TestImageTranspose(PillowTestCase):
             self.assertEqual(im.getpixel((1, y-2)), out.getpixel((1, 1)))
             self.assertEqual(im.getpixel((x-2, y-2)), out.getpixel((x-2, 1)))
 
-        for mode in ("L", "RGB"):
+        for mode in ("L", "RGB", "I;16", "I;16L", "I;16B"):
             transpose(mode)
 
     def test_rotate_90(self):
@@ -73,7 +72,7 @@ class TestImageTranspose(PillowTestCase):
             self.assertEqual(im.getpixel((1, y-2)), out.getpixel((x-2, 1)))
             self.assertEqual(im.getpixel((x-2, y-2)), out.getpixel((1, 1)))
 
-        for mode in ("L", "RGB"):
+        for mode in ("L", "RGB", "I;16", "I;16L", "I;16B"):
             transpose(mode)
 
     def test_rotate_270(self):
diff --git a/Tests/test_imageqt.py b/Tests/test_imageqt.py
index 2ded37c09..bd93828ef 100644
--- a/Tests/test_imageqt.py
+++ b/Tests/test_imageqt.py
@@ -1,7 +1,16 @@
 from .helper import PillowTestCase, hopper
 
-from PIL import ImageQt
+import warnings
 
+deprecated = False
+with warnings.catch_warnings():
+    warnings.filterwarnings("error", category=DeprecationWarning)
+    try:
+        from PIL import ImageQt
+    except DeprecationWarning:
+        deprecated = True
+        warnings.filterwarnings("ignore", category=DeprecationWarning)
+        from PIL import ImageQt
 
 if ImageQt.qt_is_installed:
     from PIL.ImageQt import qRgba
@@ -78,3 +87,6 @@ class TestImageQt(PillowQtTestCase, PillowTestCase):
     def test_image(self):
         for mode in ('1', 'RGB', 'RGBA', 'L', 'P'):
             ImageQt.ImageQt(hopper(mode))
+
+    def test_deprecated(self):
+        self.assertEqual(ImageQt.qt_version in ["4", "side"], deprecated)
diff --git a/Tests/test_pickle.py b/Tests/test_pickle.py
index 46958c085..45ef0f1db 100644
--- a/Tests/test_pickle.py
+++ b/Tests/test_pickle.py
@@ -67,9 +67,13 @@ class TestPickle(PillowTestCase):
                 "Tests/images/non_zero_bb.png",
                 "Tests/images/non_zero_bb_scale2.png",
                 "Tests/images/p_trns_single.png",
-                "Tests/images/pil123p.png"
+                "Tests/images/pil123p.png",
+                "Tests/images/itxt_chunks.png"
         ]:
-            self.helper_pickle_string(pickle, test_file=test_file)
+            for protocol in range(0, pickle.HIGHEST_PROTOCOL + 1):
+                self.helper_pickle_string(pickle,
+                                          protocol=protocol,
+                                          test_file=test_file)
 
     def test_pickle_l_mode(self):
         # Arrange
diff --git a/Tests/test_util.py b/Tests/test_util.py
index 4471b75bd..08e9c1665 100644
--- a/Tests/test_util.py
+++ b/Tests/test_util.py
@@ -1,4 +1,4 @@
-from .helper import PillowTestCase
+from .helper import unittest, PillowTestCase
 
 from PIL import _util
 
@@ -35,6 +35,18 @@ class TestUtil(PillowTestCase):
         # Assert
         self.assertTrue(it_is)
 
+    @unittest.skipIf(not _util.py36, 'os.path support for Paths added in 3.6')
+    def test_path_obj_is_path(self):
+        # Arrange
+        from pathlib import Path
+        test_path = Path('filename.ext')
+
+        # Act
+        it_is = _util.isPath(test_path)
+
+        # Assert
+        self.assertTrue(it_is)
+
     def test_is_not_path(self):
         # Arrange
         filename = self.tempfile("temp.ext")
diff --git a/azure-pipelines.yml b/azure-pipelines.yml
new file mode 100644
index 000000000..bef5eeee6
--- /dev/null
+++ b/azure-pipelines.yml
@@ -0,0 +1,67 @@
+# Python package
+# Create and test a Python package on multiple Python versions.
+# Add steps that analyze code, save the dist with the build record,
+# publish to a PyPI-compatible index, and more:
+# https://docs.microsoft.com/azure/devops/pipelines/languages/python
+
+jobs:
+
+- template: .azure-pipelines/jobs/lint.yml
+  parameters:
+    name: Lint
+    vmImage: 'Ubuntu-16.04'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'alpine'
+    name:   'alpine'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'arch'
+    name:   'arch'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'ubuntu-trusty-x86'
+    name:   'ubuntu_trusty_x86'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'ubuntu-xenial-amd64'
+    name:   'ubuntu_xenial_amd64'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'debian-stretch-x86'
+    name:   'debian_stretch_x86'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'centos-6-amd64'
+    name:   'centos_6_amd64'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'centos-7-amd64'
+    name:   'centos_7_amd64'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'amazon-1-amd64'
+    name:   'amazon_1_amd64'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'amazon-2-amd64'
+    name:   'amazon_2_amd64'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'fedora-28-amd64'
+    name:   'fedora_28_amd64'
+
+- template: .azure-pipelines/jobs/test-docker.yml
+  parameters:
+    docker: 'fedora-29-amd64'
+    name:   'fedora_29_amd64'
diff --git a/docs/deprecations.rst b/docs/deprecations.rst
index b8131ac05..fb5acfa8e 100644
--- a/docs/deprecations.rst
+++ b/docs/deprecations.rst
@@ -12,6 +12,27 @@ Deprecated features
 Below are features which are considered deprecated. Where appropriate,
 a ``DeprecationWarning`` is issued.
 
+Python 2.7
+~~~~~~~~~~
+
+.. deprecated:: 6.0.0
+
+Python 2.7 reaches end-of-life on 2020-01-01.
+
+Pillow 7.0.0 will be released on 2020-01-01 and will drop support for Python 2.7, making
+Pillow 6.x the last series to support Python 2.
+
+PyQt4 and PySide
+~~~~~~~~~~~~~~~~
+
+.. deprecated:: 6.0.0
+
+Qt 4 reached end-of-life on 2015-12-19. Its Python bindings are also EOL: PyQt4 since
+2018-08-31 and PySide since 2015-10-14.
+
+Support for PyQt4 and PySide has been deprecated from ``ImageQt`` and will be removed in
+a future version. Please upgrade to PyQt5 or PySide2.
+
 PIL.*ImagePlugin.__version__ attributes
 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
@@ -50,13 +71,12 @@ a ``DeprecationWarning``:
     Setting the size of a TIFF image directly is deprecated, and will
     be removed in a future version. Use the resize method instead.
 
-PILLOW_VERSION and VERSION constants
-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+PILLOW_VERSION constant
+~~~~~~~~~~~~~~~~~~~~~~~
 
 .. deprecated:: 5.2.0
 
-Two version constants – ``VERSION`` (the old PIL version, always 1.1.7) and
-``PILLOW_VERSION`` – have been deprecated and will be removed in the next
+``PILLOW_VERSION`` has been deprecated and will be removed in the next
 major release. Use ``__version__`` instead.
 
 Removed features
@@ -65,6 +85,14 @@ Removed features
 Deprecated features are only removed in major releases after an appropriate
 period of deprecation has passed.
 
+VERSION constant
+~~~~~~~~~~~~~~~~
+
+*Removed in version 6.0.0.*
+
+``VERSION`` (the old PIL version, always 1.1.7) has been removed. Use
+``__version__`` instead.
+
 Undocumented ImageOps functions
 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
diff --git a/docs/installation.rst b/docs/installation.rst
index abccfcf56..44cd9af6f 100644
--- a/docs/installation.rst
+++ b/docs/installation.rst
@@ -15,21 +15,23 @@ Notes
 
 .. note:: Pillow is supported on the following Python versions
 
-+--------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
-|**Python**          |**2.4**|**2.5**|**2.6**|**2.7**|**3.2**|**3.3**|**3.4**|**3.5**|**3.6**|**3.7**|
-+--------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
-|Pillow < 2.0.0      |  Yes  |  Yes  |  Yes  |  Yes  |       |       |       |       |       |       |
-+--------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
-|Pillow 2.x - 3.x    |       |       |  Yes  |  Yes  |  Yes  |  Yes  |  Yes  |  Yes  |       |       |
-+--------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
-|Pillow 4.x          |       |       |       |  Yes  |       |  Yes  |  Yes  |  Yes  |  Yes  |       |
-+--------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
-|Pillow 5.0.x - 5.1.x|       |       |       |  Yes  |       |       |  Yes  |  Yes  |  Yes  |       |
-+--------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
-|Pillow 5.2.x - 5.4.x|       |       |       |  Yes  |       |       |  Yes  |  Yes  |  Yes  |  Yes  |
-+--------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
-|Pillow >= 6.0.0     |       |       |       |  Yes  |       |       |       |  Yes  |  Yes  |  Yes  |
-+--------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
+|**Python**           |**2.4**|**2.5**|**2.6**|**2.7**|**3.2**|**3.3**|**3.4**|**3.5**|**3.6**|**3.7**|
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
+|Pillow < 2.0.0       |  Yes  |  Yes  |  Yes  |  Yes  |       |       |       |       |       |       |
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
+|Pillow 2.x - 3.x     |       |       |  Yes  |  Yes  |  Yes  |  Yes  |  Yes  |  Yes  |       |       |
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
+|Pillow 4.x           |       |       |       |  Yes  |       |  Yes  |  Yes  |  Yes  |  Yes  |       |
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
+|Pillow 5.0.x - 5.1.x |       |       |       |  Yes  |       |       |  Yes  |  Yes  |  Yes  |       |
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
+|Pillow 5.2.x - 5.4.x |       |       |       |  Yes  |       |       |  Yes  |  Yes  |  Yes  |  Yes  |
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
+|Pillow 6.x           |       |       |       |  Yes  |       |       |       |  Yes  |  Yes  |  Yes  |
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
+|Pillow >= 7.0.0      |       |       |       |       |       |       |       |  Yes  |  Yes  |  Yes  |
++---------------------+-------+-------+-------+-------+-------+-------+-------+-------+-------+-------+
 
 Basic Installation
 ------------------
diff --git a/docs/reference/ImageQt.rst b/docs/reference/ImageQt.rst
index 386401075..5128f28fb 100644
--- a/docs/reference/ImageQt.rst
+++ b/docs/reference/ImageQt.rst
@@ -7,6 +7,12 @@
 The :py:mod:`ImageQt` module contains support for creating PyQt4, PyQt5, PySide or
 PySide2 QImage objects from PIL images.
 
+Qt 4 reached end-of-life on 2015-12-19. Its Python bindings are also EOL: PyQt4 since
+2018-08-31 and PySide since 2015-10-14.
+
+Support for PyQt4 and PySide is deprecated since Pillow 6.0.0 and will be removed in a
+future version. Please upgrade to PyQt5 or PySide2.
+
 .. versionadded:: 1.1.6
 
 .. py:class:: ImageQt.ImageQt(image)
diff --git a/docs/releasenotes/6.0.0.rst b/docs/releasenotes/6.0.0.rst
index e1fa83cce..c9712ed8a 100644
--- a/docs/releasenotes/6.0.0.rst
+++ b/docs/releasenotes/6.0.0.rst
@@ -26,12 +26,38 @@ Several undocumented functions in ``ImageOps`` were deprecated in Pillow 4.3.0 (
 and have now been removed: ``gaussian_blur``, ``gblur``, ``unsharp_mask``, ``usm`` and
 ``box_blur``. Use the equivalent operations in ``ImageFilter`` instead.
 
+Removed deprecated VERSION
+^^^^^^^^^^^^^^^^^^^^^^^^^^
+
+``VERSION`` (the old PIL version, always 1.1.7) has been removed. Use ``__version__``
+instead.
+
 API Changes
 ===========
 
 Deprecations
 ^^^^^^^^^^^^
 
+Python 2.7
+~~~~~~~~~~
+
+Python 2.7 reaches end-of-life on 2020-01-01.
+
+Pillow 7.0.0 will be released on 2020-01-01 and will drop support for Python 2.7, making
+Pillow 6.x the last series to support Python 2.
+
+PyQt4 and PySide
+~~~~~~~~~~~~~~~~
+
+Qt 4 reached end-of-life on 2015-12-19. Its Python bindings are also EOL: PyQt4 since
+2018-08-31 and PySide since 2015-10-14.
+
+Support for PyQt4 and PySide has been deprecated from ``ImageQt`` and will be removed in
+a future version. Please upgrade to PyQt5 or PySide2.
+
+PIL.*ImagePlugin.__version__ attributes
+~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+
 These version constants have been deprecated and will be removed in a future
 version.
 
diff --git a/src/PIL/ContainerIO.py b/src/PIL/ContainerIO.py
index 682ad9031..e6c288c83 100644
--- a/src/PIL/ContainerIO.py
+++ b/src/PIL/ContainerIO.py
@@ -18,6 +18,8 @@
 # A file object that provides read access to a part of an existing
 # file (for example a TAR file).
 
+import io
+
 
 class ContainerIO(object):
 
@@ -39,9 +41,9 @@ class ContainerIO(object):
     # Always false.
 
     def isatty(self):
-        return 0
+        return False
 
-    def seek(self, offset, mode=0):
+    def seek(self, offset, mode=io.SEEK_SET):
         """
         Move file pointer.
 
diff --git a/src/PIL/EpsImagePlugin.py b/src/PIL/EpsImagePlugin.py
index 43dcdfb67..7421189f8 100644
--- a/src/PIL/EpsImagePlugin.py
+++ b/src/PIL/EpsImagePlugin.py
@@ -104,7 +104,7 @@ def Ghostscript(tile, size, fp, scale=1):
         # Copy whole file to read in Ghostscript
         with open(infile_temp, 'wb') as f:
             # fetch length of fp
-            fp.seek(0, 2)
+            fp.seek(0, io.SEEK_END)
             fsize = fp.tell()
             # ensure start position
             # go back
@@ -169,7 +169,7 @@ class PSFile(object):
         self.fp = fp
         self.char = None
 
-    def seek(self, offset, whence=0):
+    def seek(self, offset, whence=io.SEEK_SET):
         self.char = None
         self.fp.seek(offset, whence)
 
@@ -312,7 +312,7 @@ class EpsImageFile(ImageFile.ImageFile):
 
         if s[:4] == b"%!PS":
             # for HEAD without binary preview
-            fp.seek(0, 2)
+            fp.seek(0, io.SEEK_END)
             length = fp.tell()
             offset = 0
         elif i32(s[0:4]) == 0xC6D3D0C5:
diff --git a/src/PIL/GifImagePlugin.py b/src/PIL/GifImagePlugin.py
index 2d13de022..2ebd8b248 100644
--- a/src/PIL/GifImagePlugin.py
+++ b/src/PIL/GifImagePlugin.py
@@ -604,16 +604,16 @@ def _save_netpbm(im, fp, filename):
 
     import os
     from subprocess import Popen, check_call, PIPE, CalledProcessError
-    file = im._dump()
+    tempfile = im._dump()
 
     with open(filename, 'wb') as f:
         if im.mode != "RGB":
             with open(os.devnull, 'wb') as devnull:
-                check_call(["ppmtogif", file], stdout=f, stderr=devnull)
+                check_call(["ppmtogif", tempfile], stdout=f, stderr=devnull)
         else:
             # Pipe ppmquant output into ppmtogif
-            # "ppmquant 256 %s | ppmtogif > %s" % (file, filename)
-            quant_cmd = ["ppmquant", "256", file]
+            # "ppmquant 256 %s | ppmtogif > %s" % (tempfile, filename)
+            quant_cmd = ["ppmquant", "256", tempfile]
             togif_cmd = ["ppmtogif"]
             with open(os.devnull, 'wb') as devnull:
                 quant_proc = Popen(quant_cmd, stdout=PIPE, stderr=devnull)
@@ -632,7 +632,7 @@ def _save_netpbm(im, fp, filename):
                 raise CalledProcessError(retcode, togif_cmd)
 
     try:
-        os.unlink(file)
+        os.unlink(tempfile)
     except OSError:
         pass
 
diff --git a/src/PIL/IcnsImagePlugin.py b/src/PIL/IcnsImagePlugin.py
index 2ea66675f..4a10b24b8 100644
--- a/src/PIL/IcnsImagePlugin.py
+++ b/src/PIL/IcnsImagePlugin.py
@@ -195,7 +195,7 @@ class IcnsFile(object):
             i += HEADERSIZE
             blocksize -= HEADERSIZE
             dct[sig] = (i, blocksize)
-            fobj.seek(blocksize, 1)
+            fobj.seek(blocksize, io.SEEK_CUR)
             i += blocksize
 
     def itersizes(self):
diff --git a/src/PIL/Image.py b/src/PIL/Image.py
index bdbb7f88d..9cfb2160a 100644
--- a/src/PIL/Image.py
+++ b/src/PIL/Image.py
@@ -40,10 +40,10 @@ if False:
 
     from PyQt5.QtGui import QImage, QPixmap
 
-# VERSION is deprecated and will be removed in Pillow 6.0.0.
-# PILLOW_VERSION is deprecated and will be removed after that.
+# VERSION was removed in Pillow 6.0.0.
+# PILLOW_VERSION is deprecated and will be removed in Pillow 7.0.0.
 # Use __version__ instead.
-from . import VERSION, PILLOW_VERSION, __version__, _plugins
+from . import PILLOW_VERSION, __version__, _plugins
 from ._util import py3
 
 import logging
@@ -76,8 +76,7 @@ except ImportError:
     from collections import Callable
 
 
-# Silence warnings
-assert VERSION
+# Silence warning
 assert PILLOW_VERSION
 
 logger = logging.getLogger(__name__)
@@ -680,8 +679,7 @@ class Image(object):
 
     def __eq__(self, other):
         # type: (object) -> bool
-        return (isinstance(other, Image) and
-                self.__class__.__name__ == other.__class__.__name__ and
+        return (self.__class__ is other.__class__ and
                 self.mode == other.mode and
                 self.size == other.size and
                 self.info == other.info and
@@ -709,8 +707,7 @@ class Image(object):
 
         :returns: png version of the image as bytes
         """
-        from io import BytesIO
-        b = BytesIO()
+        b = io.BytesIO()
         self.save(b, 'PNG')
         return b.getvalue()
 
@@ -2138,10 +2135,10 @@ class Image(object):
         debugging purposes.
 
         On Unix platforms, this method saves the image to a temporary
-        PPM file, and calls either the **xv** utility or the **display**
+        PPM file, and calls the **display**, **eog** or **xv**
         utility, depending on which one can be found.
 
-        On macOS, this method saves the image to a temporary BMP file, and
+        On macOS, this method saves the image to a temporary PNG file, and
         opens it with the native Preview application.
 
         On Windows, it saves the image to a temporary BMP file, and uses
@@ -2251,11 +2248,12 @@ class Image(object):
 
         self.draft(None, size)
 
-        im = self.resize(size, resample)
+        if self.size != size:
+            im = self.resize(size, resample)
 
-        self.im = im.im
-        self.mode = im.mode
-        self._size = size
+            self.im = im.im
+            self._size = size
+            self.mode = self.im.mode
 
         self.readonly = 0
         self.pyaccess = None
diff --git a/src/PIL/ImageCms.py b/src/PIL/ImageCms.py
index 29959a83a..2cd6f33b5 100644
--- a/src/PIL/ImageCms.py
+++ b/src/PIL/ImageCms.py
@@ -950,5 +950,5 @@ def versions():
 
     return (
         VERSION, core.littlecms_version,
-        sys.version.split()[0], Image.VERSION
+        sys.version.split()[0], Image.__version__
     )
diff --git a/src/PIL/ImageFile.py b/src/PIL/ImageFile.py
index 32c5af6e8..a282280dc 100644
--- a/src/PIL/ImageFile.py
+++ b/src/PIL/ImageFile.py
@@ -525,7 +525,7 @@ def _save(im, fp, tile, bufsize=0):
         for e, b, o, a in tile:
             e = Image._getencoder(im.mode, e, a, im.encoderconfig)
             if o > 0:
-                fp.seek(o, 0)
+                fp.seek(o)
             e.setimage(im.im, b)
             if e.pushes_fd:
                 e.setfd(fp)
@@ -544,7 +544,7 @@ def _save(im, fp, tile, bufsize=0):
         for e, b, o, a in tile:
             e = Image._getencoder(im.mode, e, a, im.encoderconfig)
             if o > 0:
-                fp.seek(o, 0)
+                fp.seek(o)
             e.setimage(im.im, b)
             if e.pushes_fd:
                 e.setfd(fp)
diff --git a/src/PIL/ImageMath.py b/src/PIL/ImageMath.py
index d985877a6..68247c290 100644
--- a/src/PIL/ImageMath.py
+++ b/src/PIL/ImageMath.py
@@ -28,7 +28,7 @@ VERBOSE = 0
 
 
 def _isconstant(v):
-    return isinstance(v, int) or isinstance(v, float)
+    return isinstance(v, (int, float))
 
 
 class _Operand(object):
diff --git a/src/PIL/ImageQt.py b/src/PIL/ImageQt.py
index b747781c5..02ce6354e 100644
--- a/src/PIL/ImageQt.py
+++ b/src/PIL/ImageQt.py
@@ -20,6 +20,7 @@ from . import Image
 from ._util import isPath, py3
 from io import BytesIO
 import sys
+import warnings
 
 qt_versions = [
     ['5', 'PyQt5'],
@@ -27,6 +28,12 @@ qt_versions = [
     ['4', 'PyQt4'],
     ['side', 'PySide']
 ]
+
+WARNING_TEXT = (
+    "Support for EOL {} is deprecated and will be removed in a future version. "
+    "Please upgrade to PyQt5 or PySide2."
+)
+
 # If a version has already been imported, attempt it first
 qt_versions.sort(key=lambda qt_version: qt_version[1] in sys.modules,
                  reverse=True)
@@ -41,9 +48,13 @@ for qt_version, qt_module in qt_versions:
         elif qt_module == 'PyQt4':
             from PyQt4.QtGui import QImage, qRgba, QPixmap
             from PyQt4.QtCore import QBuffer, QIODevice
+
+            warnings.warn(WARNING_TEXT.format(qt_module), DeprecationWarning)
         elif qt_module == 'PySide':
             from PySide.QtGui import QImage, qRgba, QPixmap
             from PySide.QtCore import QBuffer, QIODevice
+
+            warnings.warn(WARNING_TEXT.format(qt_module), DeprecationWarning)
     except (ImportError, RuntimeError):
         continue
     qt_is_installed = True
@@ -67,7 +78,7 @@ def fromqimage(im):
     """
     buffer = QBuffer()
     buffer.open(QIODevice.ReadWrite)
-    # preserve alha channel with png
+    # preserve alpha channel with png
     # otherwise ppm is more friendly with Image.open
     if im.hasAlphaChannel():
         im.save(buffer, 'png')
diff --git a/src/PIL/Jpeg2KImagePlugin.py b/src/PIL/Jpeg2KImagePlugin.py
index ab01845c7..9645f8ef0 100644
--- a/src/PIL/Jpeg2KImagePlugin.py
+++ b/src/PIL/Jpeg2KImagePlugin.py
@@ -193,9 +193,9 @@ class Jpeg2KImageFile(ImageFile.ImageFile):
             fd = -1
             try:
                 pos = self.fp.tell()
-                self.fp.seek(0, 2)
+                self.fp.seek(0, io.SEEK_END)
                 length = self.fp.tell()
-                self.fp.seek(pos, 0)
+                self.fp.seek(pos)
             except Exception:
                 length = -1
 
diff --git a/src/PIL/PcfFontFile.py b/src/PIL/PcfFontFile.py
index 471d6647a..b50fe72da 100644
--- a/src/PIL/PcfFontFile.py
+++ b/src/PIL/PcfFontFile.py
@@ -16,6 +16,7 @@
 # See the README file for information on usage and redistribution.
 #
 
+import io
 from . import Image, FontFile
 from ._binary import i8, i16le as l16, i32le as l32, i16be as b16, i32be as b32
 
@@ -117,7 +118,7 @@ class PcfFontFile(FontFile.FontFile):
         for i in range(nprops):
             p.append((i32(fp.read(4)), i8(fp.read(1)), i32(fp.read(4))))
         if nprops & 3:
-            fp.seek(4 - (nprops & 3), 1)  # pad
+            fp.seek(4 - (nprops & 3), io.SEEK_CUR)  # pad
 
         data = fp.read(i32(fp.read(4)))
 
diff --git a/src/PIL/PcxImagePlugin.py b/src/PIL/PcxImagePlugin.py
index 57d8189dd..8094a2866 100644
--- a/src/PIL/PcxImagePlugin.py
+++ b/src/PIL/PcxImagePlugin.py
@@ -25,6 +25,7 @@
 # See the README file for information on usage and redistribution.
 #
 
+import io
 import logging
 from . import Image, ImageFile, ImagePalette
 from ._binary import i8, i16le as i16, o8, o16le as o16
@@ -82,7 +83,7 @@ class PcxImageFile(ImageFile.ImageFile):
         elif version == 5 and bits == 8 and planes == 1:
             mode = rawmode = "L"
             # FIXME: hey, this doesn't work with the incremental loader !!!
-            self.fp.seek(-769, 2)
+            self.fp.seek(-769, io.SEEK_END)
             s = self.fp.read(769)
             if len(s) == 769 and i8(s[0]) == 12:
                 # check if the palette is linear greyscale
diff --git a/src/PIL/PdfParser.py b/src/PIL/PdfParser.py
index a7773ef1e..8f90b668d 100644
--- a/src/PIL/PdfParser.py
+++ b/src/PIL/PdfParser.py
@@ -269,18 +269,13 @@ class PdfDict(UserDict):
             else:
                 self.__dict__[key] = value
         else:
-            if isinstance(key, str):
-                key = key.encode("us-ascii")
-            self[key] = value
+            self[key.encode("us-ascii")] = value
 
     def __getattr__(self, key):
         try:
-            value = self[key]
+            value = self[key.encode("us-ascii")]
         except KeyError:
-            try:
-                value = self[key.encode("us-ascii")]
-            except KeyError:
-                raise AttributeError(key)
+            raise AttributeError(key)
         if isinstance(value, bytes):
             value = decode_text(value)
         if key.endswith("Date"):
@@ -361,8 +356,7 @@ def pdf_repr(x):
         return b"false"
     elif x is None:
         return b"null"
-    elif (isinstance(x, PdfName) or isinstance(x, PdfDict) or
-          isinstance(x, PdfArray) or isinstance(x, PdfBinary)):
+    elif isinstance(x, (PdfName, PdfDict, PdfArray, PdfBinary)):
         return bytes(x)
     elif isinstance(x, int):
         return str(x).encode("us-ascii")
diff --git a/src/PIL/PngImagePlugin.py b/src/PIL/PngImagePlugin.py
index ee080fae9..b383e17f0 100644
--- a/src/PIL/PngImagePlugin.py
+++ b/src/PIL/PngImagePlugin.py
@@ -193,7 +193,7 @@ class iTXt(str):
 
     """
     @staticmethod
-    def __new__(cls, text, lang, tkey):
+    def __new__(cls, text, lang=None, tkey=None):
         """
         :param cls: the class to use when creating the instance
         :param text: value for this key
diff --git a/src/PIL/PpmImagePlugin.py b/src/PIL/PpmImagePlugin.py
index 750454dc5..e3e411cad 100644
--- a/src/PIL/PpmImagePlugin.py
+++ b/src/PIL/PpmImagePlugin.py
@@ -70,7 +70,14 @@ class PpmImageFile(ImageFile.ImageFile):
         s = self.fp.read(1)
         if s != b"P":
             raise SyntaxError("not a PPM file")
-        mode = MODES[self._token(s)]
+        magic_number = self._token(s)
+        mode = MODES[magic_number]
+
+        self.custom_mimetype = {
+            b"P4": "image/x-portable-bitmap",
+            b"P5": "image/x-portable-graymap",
+            b"P6": "image/x-portable-pixmap",
+        }.get(magic_number)
 
         if mode == "1":
             self.mode = "1"
@@ -158,3 +165,5 @@ Image.register_open(PpmImageFile.format, PpmImageFile, _accept)
 Image.register_save(PpmImageFile.format, _save)
 
 Image.register_extensions(PpmImageFile.format, [".pbm", ".pgm", ".ppm"])
+
+Image.register_mime(PpmImageFile.format, "image/x-portable-anymap")
diff --git a/src/PIL/PsdImagePlugin.py b/src/PIL/PsdImagePlugin.py
index c631f41cb..6623f8f87 100644
--- a/src/PIL/PsdImagePlugin.py
+++ b/src/PIL/PsdImagePlugin.py
@@ -20,6 +20,7 @@
 # PIL.__version__ instead.
 __version__ = "0.4"
 
+import io
 from . import Image, ImageFile, ImagePalette
 from ._binary import i8, i16be as i16, i32be as i32
 
@@ -216,12 +217,12 @@ def _layerinfo(file):
         if size:
             length = i32(read(4))
             if length:
-                file.seek(length - 16, 1)
+                file.seek(length - 16, io.SEEK_CUR)
             combined += length + 4
 
             length = i32(read(4))
             if length:
-                file.seek(length, 1)
+                file.seek(length, io.SEEK_CUR)
             combined += length + 4
 
             length = i8(read(1))
@@ -231,7 +232,7 @@ def _layerinfo(file):
                 name = read(length).decode('latin-1', 'replace')
             combined += length + 1
 
-        file.seek(size - combined, 1)
+        file.seek(size - combined, io.SEEK_CUR)
         layers.append((name, mode, (x0, y0, x1, y1)))
 
     # get tiles
diff --git a/src/PIL/TarIO.py b/src/PIL/TarIO.py
index 89957fba4..a421b12a5 100644
--- a/src/PIL/TarIO.py
+++ b/src/PIL/TarIO.py
@@ -14,6 +14,7 @@
 # See the README file for information on usage and redistribution.
 #
 
+import io
 import sys
 from . import ContainerIO
 
@@ -51,7 +52,7 @@ class TarIO(ContainerIO.ContainerIO):
             if file == name:
                 break
 
-            self.fh.seek((size + 511) & (~511), 1)
+            self.fh.seek((size + 511) & (~511), io.SEEK_CUR)
 
         # Open region
         ContainerIO.ContainerIO.__init__(self, self.fh, self.fh.tell(), size)
diff --git a/src/PIL/TiffImagePlugin.py b/src/PIL/TiffImagePlugin.py
index 195c87f91..cea1b0ba4 100644
--- a/src/PIL/TiffImagePlugin.py
+++ b/src/PIL/TiffImagePlugin.py
@@ -135,6 +135,9 @@ COMPRESSION_INFO = {
     32946: "tiff_deflate",
     34676: "tiff_sgilog",
     34677: "tiff_sgilog24",
+    34925: "lzma",
+    50000: "zstd",
+    50001: "webp",
 }
 
 COMPRESSION_INFO_REV = {v: k for k, v in COMPRESSION_INFO.items()}
@@ -423,7 +426,7 @@ class ImageFileDirectory_v2(MutableMapping):
 
         ifd = ImageFileDirectory_v2()
         ifd[key] = 'Some Data'
-        ifd.tagtype[key] = 2
+        ifd.tagtype[key] = TiffTags.ASCII
         print(ifd[key])
         'Some Data'
 
@@ -557,7 +560,7 @@ class ImageFileDirectory_v2(MutableMapping):
             if info.type:
                 self.tagtype[tag] = info.type
             else:
-                self.tagtype[tag] = 7
+                self.tagtype[tag] = TiffTags.UNDEFINED
                 if all(isinstance(v, IFDRational) for v in values):
                     self.tagtype[tag] = TiffTags.RATIONAL
                 elif all(isinstance(v, int) for v in values):
@@ -872,7 +875,7 @@ class ImageFileDirectory_v1(ImageFileDirectory_v2):
 
         ifd = ImageFileDirectory_v1()
         ifd[key] = 'Some Data'
-        ifd.tagtype[key] = 2
+        ifd.tagtype[key] = TiffTags.ASCII
         print(ifd[key])
         ('Some Data',)
 
@@ -1436,7 +1439,7 @@ def _save(im, fp, filename):
         try:
             ifd.tagtype[key] = info.tagtype[key]
         except Exception:
-            pass  # might not be an IFD, Might not have populated type
+            pass  # might not be an IFD. Might not have populated type
 
     # additions written by Greg Couch, gregc@cgl.ucsf.edu
     # inspired by image-sig posting from Kevin Cazabon, kcazabon@home.com
@@ -1680,7 +1683,7 @@ class AppendingTiffWriter:
     def tell(self):
         return self.f.tell() - self.offsetOfNewPage
 
-    def seek(self, offset, whence):
+    def seek(self, offset, whence=io.SEEK_SET):
         if whence == os.SEEK_SET:
             offset += self.offsetOfNewPage
 
diff --git a/src/PIL/__init__.py b/src/PIL/__init__.py
index bc8cfed8c..ec0611b68 100644
--- a/src/PIL/__init__.py
+++ b/src/PIL/__init__.py
@@ -16,10 +16,9 @@ PIL.VERSION is the old PIL version and will be removed in the future.
 
 from . import _version
 
-# VERSION is deprecated and will be removed in Pillow 6.0.0.
-# PILLOW_VERSION is deprecated and will be removed after that.
+# VERSION was removed in Pillow 6.0.0.
+# PILLOW_VERSION is deprecated and will be removed in Pillow 7.0.0.
 # Use __version__ instead.
-VERSION = '1.1.7'  # PIL Version
 PILLOW_VERSION = __version__ = _version.__version__
 
 del _version
diff --git a/src/PIL/_util.py b/src/PIL/_util.py
index 5828c2c24..cb307050c 100644
--- a/src/PIL/_util.py
+++ b/src/PIL/_util.py
@@ -2,13 +2,20 @@ import os
 import sys
 
 py3 = sys.version_info.major >= 3
+py36 = sys.version_info[0:2] >= (3, 6)
 
 if py3:
     def isStringType(t):
         return isinstance(t, str)
 
-    def isPath(f):
-        return isinstance(f, (bytes, str))
+    if py36:
+        from pathlib import Path
+
+        def isPath(f):
+            return isinstance(f, (bytes, str, Path))
+    else:
+        def isPath(f):
+            return isinstance(f, (bytes, str))
 else:
     def isStringType(t):
         return isinstance(t, basestring)  # noqa: F821
diff --git a/src/libImaging/Geometry.c b/src/libImaging/Geometry.c
index 1d08728da..5358f6eeb 100644
--- a/src/libImaging/Geometry.c
+++ b/src/libImaging/Geometry.c
@@ -39,7 +39,11 @@ ImagingFlipLeftRight(Imaging imOut, Imaging imIn)
     ImagingSectionEnter(&cookie);
 
     if (imIn->image8) {
-        FLIP_LEFT_RIGHT(UINT8, image8)
+        if (strncmp(imIn->mode, "I;16", 4) == 0) {
+            FLIP_LEFT_RIGHT(UINT16, image8)
+        } else {
+            FLIP_LEFT_RIGHT(UINT8, image8)
+        }
     } else {
         FLIP_LEFT_RIGHT(INT32, image32)
     }
@@ -253,7 +257,11 @@ ImagingRotate180(Imaging imOut, Imaging imIn)
 
     yr = imIn->ysize-1;
     if (imIn->image8) {
-        ROTATE_180(UINT8, image8)
+        if (strncmp(imIn->mode, "I;16", 4) == 0) {
+            ROTATE_180(UINT16, image8)
+        } else {
+            ROTATE_180(UINT8, image8)
+        }
     } else {
         ROTATE_180(INT32, image32)
     }